Z. Zhu

The paper introduces a micropatterned nanocomposite platform called CellWell for culturing chondrocytes that supports high-throughput single-cell analysis and maintains physiological morphology.

The paper analyzes 12 Shigella sonnei strains to compare virulence and antibiotic resistance, finding that resistant strains have more virulence factors and distinct genetic clusters.

This study evaluates the antiviral activity of nucleoside ProTides against Zika virus in human neural stem cells, identifying effective compounds and elucidating their mechanism of action.

This study investigates how methotrexate inhibits Zika virus replication by targeting the dihydrofolate reductase pathway and shows that adenosine depletion also contributes to its antiviral effect.

This study identifies genome-wide nucleotide sites associated with mammalian virulence in influenza A viruses and develops machine-learning models to predict virulence.

This study investigates how palbociclib and fulvestrant affect metabolic pathways in breast cancer cells, finding synergistic effects when combined.

The paper develops and validates a high-content imaging assay to assess antiviral activity of small-molecule inhibitors against Zika virus by detecting cytopathic effects.

The paper curates a database of virus-host receptor interactions and identifies common features of viral receptors, showing their role in cross-species transmission.

The paper investigates the role of minor alleles in schizophrenia using public datasets, finding higher minor allele content in cases and identifying SNPs that predict schizophrenia with 100% certainty.