Author

F. Gu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Bioengineering· 1 Cell Biology· 1 Pathology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 3 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Organism:plant (other)· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

A. Adams· 2 shared E. Nielsen· 2 shared H. B. Mayes· 2 shared J. Yang· 2 shared L. Wang· 2 shared Y. Li· 2 shared Y. Wang· 2 shared Z. Zhu· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

A. Adams

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Metatranscriptomic analysis indicates prebiotic effect of Isomalto/malto-polysaccharides on human colonic microbiota in-vitro

K. Borewicz, B. V. H. Hornung, F. Gu, P. H. van der Zaal, H. A. Schols, P. J. Schaap, H. Smidt

This study uses metatranscriptomics to show that IMMPs with more (1→6) glycosidic linkages increase gene expression in Bacteroides, Lactobacillus, and Bifidobacterium, leading to higher SCFA production in human fecal microbiota.

bioRxiv · Dec 31, 2023 · PreprintMicrobiology

Functional Relations of CSLD2, CSLD3, and CSLD5 Proteins during Cell Wall Synthesis in Arabidopsis

J. Yang, A. Sahu, A. Adams, S. Yin, F. Gu, H. B. Mayes, E. Nielsen

This study investigates the functional roles of CSLD2, CSLD3, and CSLD5 proteins in cell wall synthesis in Arabidopsis, showing their conserved {beta}-1,4 glucan synthase activities and distinct contributions to cell plate formation.

bioRxiv · Apr 25, 2023 · PreprintCell Biology

A Genome-scale Screen Reveals ANTXR1, Heparan Sulfate and Neu5Gc as Host Factors mediating Seneca Valley virus Entry into Porcine Cells

W. Tang, Y. Wang, X. Qi, F. Gu, K. Li, H. Han, X. Du, Z. Zhu, S. Wu, Y. Zhao, h. zheng

This study identifies ANTXR1, heparan sulfate, and Neu5Gc as host factors required for SVV entry into porcine cells using CRISPR screening.

bioRxiv · Jun 14, 2022 · PreprintPathology

A microfluidic droplet array demonstrating high-throughput screening in individual lipid-producing microalgae

G. Zheng, F. Gu, Y. Cui, L. Lu, X. Hu, L. Wang, Y. Wang

The paper develops a microfluidic droplet array for high-throughput screening of lipid-producing microalgae, enabling real-time monitoring and identification of individual cells under different conditions.

bioRxiv · May 5, 2022Bioengineering

A Cyclic Phosphoramidate Prodrug of 2-deoxy-2-fluoro-2-C-methylguanosine for the Treatment of Dengue Infection

R. Karuna, F. Yokokawa, K. Wang, J. Zhang, H. Xu, G. Wang, M. Ding, W. L. Chan, N. Abdul Ghafar, A. Leonardi, C. C. Seh, P. G. Seah, W. Liu, S. P. S. Rao, S. P. Lim, , Y.-L. Chen

This paper identifies a cyclic phosphoramidate prodrug that shows anti-dengue activity in vitro and in vivo but is suspended due to toxicity concerns.

Antimicrobial Agents and Chemotherapy · Nov 17, 2020Peer-reviewedMicrobiology

Functional Characterization of fer-ts, a ts- FERONIA Mutant Allele That Alters Root Hair Growth

D. Kim, J. Yang, F. Gu, S. Park, J. Combs, A. Adams, H. B. Mayes, E. Nielsen

This paper identifies a temperature-sensitive fer-ts mutant of FERONIA that affects root hair growth and hormone responses, with altered protein turnover and ROS accumulation at elevated temperatures.

bioRxiv · May 27, 2020 · PreprintPlant Biology

Comparative genome analysis of 12 Shigella sonnei strains: virulence, resistance, and their interactions

Z. Zhu, L. Wang, F. Gu, Y. Li, H. Zhang, Y. Chen, J. Shi, P. Ma, B. Gu

The paper analyzes 12 Shigella sonnei strains to compare virulence and antibiotic resistance, finding that resistant strains have more virulence factors and distinct genetic clusters.

bioRxiv · Feb 8, 2019Microbiology

CHOP and IRE1α-XBP1/JNK signaling promote Newcastle Disease Virus induced apoptosis and benefit virus proliferation

Y. Li, Y. Liao, Q. Niu, F. Gu, Y. Sun, C. Meng, L. Tan, C. Song, X. Qiu, C. Ding

This study identifies CHOP and IRE1α-XBP1/JNK signaling as mediators of NDV-induced apoptosis and their role in promoting virus proliferation in tumor cells.

bioRxiv · Apr 12, 2018Microbiology