A. Singh

This paper constructs a single-cell transcriptome atlas of colorectal cancer to reveal subclonal heterogeneity and identify CAF subtypes associated with survival and immunotherapy resistance.

This study shows that H3K27me3 promotes TNBC peritoneal metastasis by upregulating KRT14 through repression of Sp1, and suggests tazemetostat as a potential therapeutic target.

This study analyzes stochastic dynamics in predator-prey models, showing how attack rate sensitivity affects population fluctuations and reveals distinct signatures based on density-dependent mechanisms.

This study identifies miR775 and its target GALT9 as regulators of submergence-induced senescence recovery in Arabidopsis by modulating SAGs and ROS levels.

This study identifies miR775 as a regulator of growth and development in Arabidopsis thaliana by targeting a β-(1,3)-galactosyltransferase, affecting rosette size and responding to UV-B and hypoxia.

The paper shows that reduced miR158 activity in Arabidopsis leads to 21-nucleotide tertiary phasiRNA generation targeting NHX2, affecting transpiration and stomatal conductance.

The paper develops a high-throughput FTHFS gene sequencing method and compares it with T-RFLP and 16S rRNA profiling to study acetogenic community dynamics in anaerobic digesters.

This study models how a parasitoid with Type III functional response stabilizes multi-host communities, showing that acceleration in attack rate can stabilize population dynamics.

This study shows that optimal heterogeneity in parasitism risk and Type III functional responses can stabilize host-parasitoid dynamics by altering population density correlations.

The paper shows that glycolysis downregulation is a hallmark of HIV-1 latency and that targeting antioxidant pathways can reactivate latent HIV-1.

The paper develops a discrete-time model for two competing parasitoid species on a shared host, showing coexistence conditions based on host reproduction rate and competition response sensitivity.

This paper shows that the Drosophila odor receptor coreceptor (Orco) enters olfactory cilia in two stages post-eclosion and is localized to the distal ciliary domain by the kinesin-2 motor complex.

The paper develops a novel antibody to detect L1ORF2p, showing its expression in murine germ tissues and human oral squamous cell carcinoma samples.

The paper introduces a benchmark dataset for evaluating individual tree crown delineation algorithms using co-registered remote sensing data and provides an R package for standardized evaluation.

This study evaluates the efficacy of STI-2020 antibody delivered post-infection via intranasal or intravenous routes in a hamster model of COVID-19, showing reduced disease severity and duration.

The paper demonstrates that NC410, a LAIR-2 Fc protein, blocks LAIR-1-collagen interaction, enhancing T cell activity and reducing tumor growth in humanized models.

This study demonstrates that chitosan-coated outer membrane vesicles (OMVs) from Campylobacter jejuni induce strong immune responses and reduce cecal colonization in mice, suggesting their potential as a vaccine platform.

The paper introduces SNAP, a deep learning pipeline for automated soybean nodule quantification with 99% accuracy, enabling efficient analysis of nodule traits and genetic-environmental interactions.

This study shows that TLR3 ligand promotes breast cancer cell proliferation via the MyD88-Cyclin D1 pathway, with MyD88 inhibition blocking this effect.

The paper shows that aging enhances innate immune responses to bacterial infections in mice but persistent inflammation leads to host mortality.

The paper introduces a dataset of 100 million individual tree crowns derived from remote sensing and deep learning, enabling large-scale forest analysis.

This study identifies disulfiram as a novel inhibitor of Mtb's methionine biosynthesis, showing anti-tubercular effects through redox disruption and immune modulation.

This study identifies drug-tolerant persisters (DTPs) in HER2+ breast cancer and reveals their origins and vulnerabilities to TKI resistance.

This study identifies the YKI-CACTUS(IKBα)-JNK axis as a driver of tumor growth and progression in Drosophila by linking oncogenic Yki to inflammatory signaling.

This paper demonstrates that vanadium pentoxide nanosheets act as antioxidant nanozymes to counteract HIV-1 by modulating redox potential and inhibiting viral reactivation and Mtb proliferation.

This paper shows that Mtb's SufR senses NO via its 4Fe-4S cluster, regulates Fe-S cluster biogenesis, and supports persistence in mice.

The paper shows that HIV-1 reactivation from latency is regulated by a transient heritable memory in T cells, revealed through fluctuation assays and mathematical modeling.

This study identifies a neutrophil subset responsible for ALI in sepsis and shows that targeting it with nanotherapeutics prevents ALI without harming host defense.

This study applies spatial mark-resight models to estimate leopard densities in Manas National Park, incorporating both melanistic and wild phenotypes using camera trap data.

This paper presents a jurisdictional observation network integrating satellite remote sensing and volunteer-based trail cameras to improve wildlife monitoring and management.