Author

G.-D. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 3 Assay:whole-genome sequencing· 3 Research Focus:development & morphogenesis· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

G. Li· 2 shared Q. Fu· 2 shared X. Wang· 2 shared Y.-P. Zhang· 2 shared A. D. Poyarkov· 1 shared A. Esmailizadeh· 1 shared B. Mao· 1 shared B.-W. Zhou· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersEvolutionary Biology

G. Li

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Determinants of de novo mutations in extended pedigrees of 43 dog breeds

S.-J. Zhang, J. Ma, M. Riera, S. Besenbacher, J. Niskanen, N. Salokorpi, S. Hundi, M. K. Hytonen, T. Zhou, G. Li, E. A. Ostrander, M. Schierup, H. Lohi, G.-D. Wang

The paper investigates mutation rates in 43 dog breeds, finding stable rates influenced by parental age and breed-specific differences in mutation accumulation.

bioRxiv · Jun 4, 2024Evolutionary Biology

Single-nuclei transcriptomics of dog hippocampus reveals the distinct cellular mechanism of domestication

Q.-J. Zhou, X. Liu, L. Zhang, R. Wang, T. Yin, X. Li, G. Li, Y. He, Z. Ding, P. Ma, S.-Z. Wang, B. Mao, S. Zhang, G.-D. Wang

This study uses single-nuclei transcriptomics to analyze dog hippocampus cell types and identifies convergence between differentially expressed genes and putative positively selected genes related to nervous system development.

bioRxiv · Jan 29, 2022 · PreprintEvolutionary Biology

Homo-harringtonine (HHT) - A highly effective drug against coronaviruses and the potential for large-scale clinical applications

H.-J. Wen, P. Lin, G.-X. Zhong, Z.-C. Xu, L. Shuai, Z.-Y. Wen, C. Wang, X. Cao, W.-B. He, J. Feng, Q.-C. Cai, H.-J. Ma, S.-J. Wu, G.-D. Wang, X.-M. Lyu, , C.-I. Wu

The paper identifies Homo-harringtonine (HHT) as a potent antiviral drug against coronaviruses, effective in mouse models and safe in dogs, with potential for large-scale clinical use.

bioRxiv · Apr 16, 2021 · PreprintMicrobiology

Genomic approaches reveal an endemic sub-population of gray wolves in Southern China

G.-D. Wang, M. Zhang, X. Wang, M. A. Yang, P. Cao, F. Liu, H. Lu, X. Feng, P. Skoglund, L. Wang, Q. Fu, Y.-P. Zhang

The paper analyzes ancient DNA from museum specimens to show that Southern Chinese gray wolves form a distinct sub-population with genetic links to an extinct canid related to dholes.

bioRxiv · Jan 8, 2019Evolutionary Biology

Canine transmissible venereal tumor genome reveals ancient introgression from coyotes to arctic sled dogs

X. Wang, B.-W. Zhou, T.-T. Yin, F.-L. Chen, A. Esmailizadeh, M. M. Turner, A. D. Poyarkov, P. Savolainen, G.-D. Wang, Q. Fu, Y.-P. Zhang

bioRxiv · Jun 19, 2018 · PreprintEvolutionary Biology