K. Murata

Use of phase plate cryo-EM reveals conformation diversity of therapeutic IgG with 50 kDa Fab fragment resolved below 6 angstrom

This study uses phase plate cryo-EM to reveal conformational diversity in therapeutic IgG, achieving sub-nanometer resolution of the Fab fragment.

A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta

This paper introduces a novel genetic mouse model of aortic dissection showing immune cell infiltration and altered ECM dynamics.

Effects of diet particle size on growth performance of the edible cricket, Teleogryllus occipitalis (Orthoptera: Gryllidae)

This study examines how diet particle size affects growth performance in edible crickets, finding that granular feed promotes better growth than powdered feed.

Highly efficient transgenic mouse production using piggyBac and its application to rapid phenotyping at the founder generation

This study improves transgenic mouse production efficiency using piggyBac, enabling phenotyping in the founder generation and demonstrating application with bacterial artificial chromosome transgenes.

Structure and function of bacterial YeeE-YeeD complex in thiosulfate uptake pathway

This study investigates the YeeE-YeeD complex in thiosulfate uptake, showing YeeD's role in transport and decomposition, and presents their structural interactions.

Post-acquisition super resolution for cryo-electron microscopy

The paper introduces a post-acquisition super resolution method for cryo-EM that exceeds the physical Nyquist limit by pixel doubling pre-processing, applicable to various viral and protein datasets.

Biochemical reactions between intra-articular tissues and joint instability in a rat model of osteoarthritis

This study investigates the role of joint instability in osteoarthritis progression using a rat model, finding that joint instability exacerbates cartilage degeneration and that TGF-β1 inhibition may reduce synovial inflammation.

Structure and its transformation of elliptical nege-like virus Tanay virus

This study determines the cryo-EM structure of Tanay virus and reveals its dynamic shape changes under different conditions, suggesting structural roles in infection and assembly.

The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers

This paper reports the structure and function of the photosystem I supercomplex in Ostreococcus tauri, showing it assembles with light-harvesting complexes and exhibits reversible photoacclimation.

Oxytocin and Emotional Tear in Dogs

This study investigates the relationship between emotional arousal, tear volume, and oxytocin in dogs, finding that oxytocin increases tear volume during emotional reunions with owners.

Particle morphology of medusavirus inside and outside the cells reveals a new maturation process of giant viruses

The paper investigates medusavirus morphology and maturation using electron microscopy, revealing a new maturation process with distinct particle types and structural features.

BITC induces cardiomyocyte proliferation and heart regeneration

This study shows that BITC induces cardiomyocyte proliferation and heart regeneration in neonatal and adult mice through CDK pathway activation and hypoxia-related signaling.

The 4.4 A structure of the giant Melbournevirus virion belonging to the Marseilleviridae family

The paper reports the 4.4 Å cryo-EM structure of the Melbournevirus capsid, revealing structural features and protein organization unique to the Marseilleviridae family.

Desiccation-induced fibrous condensation of CAHS protein from an anhydrobiotic tardigrade

This study investigates the self-assembling properties of CAHS1 protein from tardigrades under desiccation conditions, showing it forms hydrogels and condensates that may contribute to desiccation tolerance.

Effect of differences in mechanical stress in vivo on the onset and progression of knee osteoarthritis

This study investigates how different types of mechanical stress affect knee osteoarthritis onset and progression using animal models.

Effect of Suppression of Rotational Joint Instability on Cartilage and Meniscus Degeneration in Mouse Osteoarthritis Model

This study compares the effects of two knee instability models on cartilage and meniscus degeneration in mice, finding that reducing rotational instability suppresses cartilage degeneration.

Nasal delivery of single-domain antibodies improve symptoms of SARS-CoV-2 infection in an animal model

This paper shows nasal delivery of a camelid single-domain antibody reduces SARS-CoV-2 titers in hamsters without weight loss or cytokine induction.

Structural basis of LhcbM5-mediated state transitions in green algae

The paper reports high-resolution structures of PSI-LHCI-LHCII supercomplex in green algae, revealing the role of LhcbM5 in state transitions and supercomplex formation.

Atomic structure of human sapovirus capsid by single particle cryo-electron microscopy

The paper reports the atomic structure of human sapovirus capsid using cryo-EM, revealing domain interactions and hypervariable regions important for immune response and receptor binding.

A novel capsid protein network allows the characteristic inner membrane structure of Marseilleviridae giant viruses

The paper investigates the structure of tokyovirus, a Marseilleviridae giant virus, revealing a novel capsid protein network that forms its characteristic inner membrane structure.

Characterization of amyloid β fibril formation under microgravity conditions

This study examines amyloid β fibril formation under microgravity conditions on the ISS, finding slower progression and distinct morphologies compared to ground-based experiments.

Dynamic rotation of the protruding domain enhances the infectivity of norovirus

This study shows that the protruding domain of norovirus capsids dynamically rotates between rising and resting conformations in response to pH and metal ions, enhancing infection efficiency.

Cables2 Is a novel Smad2-regulatory factor essential for early embryonic development in mice

This study identifies Cables2 as a Smad2-regulatory factor required for early embryonic development in mice, showing its role in gastrulation and gene expression patterns.

Isolation of an archaeon at the prokaryote-eukaryote interface

The paper isolates an Asgard archaeon and proposes a symbiosis model for eukaryogenesis based on its morphology and metabolism.

Streptococcal phosphotransferase system imports unsaturated hyaluronan disaccharide derived from host extracellular matrices

This paper identifies the streptococcal phosphotransferase system (PTS) as the importer of unsaturated hyaluronan disaccharide, a fragmented form of host extracellular matrix glycosaminoglycan.

Demonstration of the potential of environmental DNA as a tool for the detection of avian species

The paper demonstrates that environmental DNA (eDNA) metabarcoding using MiBird primers can detect avian species from water samples, showing potential as a complementary tool for bird monitoring.

Cryo-EM Of A Marseilleviridae Virus Particle Reveals A Large Internal Microassembly

The paper presents a cryo-EM structure of the Marseilleviridae virus Melbournevirus, revealing a large internal microassembly and structural complexity.