L. Hu

This paper identifies and characterizes ittA, an intergenic sRNA in Borrelia burgdorferi, showing its role in infectivity and tissue tropism through genetic inactivation and transcriptomic/proteomic analyses.

This paper introduces an acoustofluidic device to create 3D neurospheroids for modeling Alzheimer's disease neuroinflammation and amyloid-β toxicity.

This study shows that silicon enhances plant resistance against powdery mildew through distinct, multi-layered defense mechanisms involving PAD4-dependent and SA-independent pathways.

This study shows SPARC enhances insulin secretion by reducing RGS4 in pancreatic beta-cells, improving glucose tolerance in SPARC-deficient mice.

This study determines the structure of hDGAT1 with a substrate, revealing its homodimeric organization and substrate-binding sites.

This study investigates the intestinal absorption of morroniside using a Caco-2 cell model, finding pH- and temperature-dependent transport and involvement of efflux proteins.

The paper investigates how entomopathogenic nematodes develop resistance to benzoxazinoid metabolites sequestered by a maize herbivore, showing increased infectivity towards the herbivore.

This study identifies BCAT1-mediated metabolic reprogramming as a mechanism of EGFR TKI resistance in lung cancer and shows that combining TKI with ROS-inducing agents can overcome resistance.

This study shows entomopathogenic nematodes attract healthy herbivores to infected cadavers via specific volatiles, enhancing their ability to control pest populations.

This study shows that indole, a volatile compound, primes early defense signaling in rice, enhancing resistance to herbivores by upregulating key signaling components like OsMPK3 and OsWRKY70.

This paper introduces a method to generate DNA methylation variation in Arabidopsis thaliana by expressing a human TET enzyme, leading to hypomethylation and phenotypic changes.

This study identifies LINC00844 as an androgen-regulated lncRNA that suppresses prostate cancer migration and invasion by modulating AR chromatin binding and NDRG1 expression.