B. Tan

Design of SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

The paper designs SARS-CoV-2 PLpro inhibitors that show antiviral efficacy in a mouse model against SARS-CoV-2 and its variants.

A Hybrid Transistor with Transcriptionally Controlled Computation and Plasticity

This paper describes hybrid OECTs with Shewanella oneidensis that translate biological computation into electrical responses using transcriptional control of extracellular electron transfer.

Light-evoked deformations in rod photoreceptors, pigment epithelium and subretinal space revealed by prolonged and multilayered optoretinography

This paper introduces a new optoretinography technique that detects light-evoked deformations in multiple retinal structures, including rods, pigment epithelium, and subretinal space, with high sensitivity and spatial resolution.

Phase-Restoring Subpixel Image Registration: Enhancing Motion Detection Performance in Fourier-domain Optical Coherence Tomography

This paper introduces PRESIR, a method to correct motion-related decorrelation noise in FD-OCT, improving motion detection sensitivity and accuracy.

Distribution of Critical Areas for Ecological Conservation in Multiple Scenarios ---- Emphasizing the Impact of Human Activities

This study identifies critical ecological protection areas in Aksu City and Wensu County by simulating human activity impacts and analyzing resistance surfaces across different scenarios.

The connection between Rap1 and Talin1 in CD4+ T Lymphocytes

This study investigates the role of Rap1-talin1 interactions and RIAM in integrin activation in CD4+ T cells, showing that RIAM can substitute for Rap1 binding in some contexts.

Remdesivir inhibits renal fibrosis in obstructed kidneys

This study shows remdesivir reduces renal fibrosis in obstructed kidneys without affecting renal or liver function.

Admistration of Exogenous Melatonin Improves the Diurnal Rhythms of Gut Microbiota in High Fat Diet-Fed Mice

This study shows that exogenous melatonin administration restores diurnal rhythms in gut microbiota and host metabolism in high fat diet-fed mice.

Quantitative proximity proteomics resolves the epithelial apical-lateral border and uncovers a vertebrate marginal zone defined by the polarity protein Pals1

The paper uses proximity proteomics to map the apical-lateral border in MDCK-II cells, identifying a new membrane compartment defined by Pals1.

A major locus controls local adaptation and adaptive life history variation in a perennial plant

The paper identifies a major genetic locus, PtFT2, that controls local adaptation and adaptive life history variation in European aspen across a latitudinal gradient.

Vitamin and amino acid auxotrophy in anaerobic consortia operating under methanogenic condition

The paper investigates microbial consortia under methanogenic conditions, revealing auxotrophy for vitamins and amino acids and complex interactions beyond traditional syntrophy.