Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
X. Wang, S. Su, Y. Zhu, X. Cheng, C. Chen, L. Chen, A. Lei, L. Zhang, Y. Xu, W. Li, Y. Zhang, D. Ye, J. ZHANG
This study shows that targeting ACOD1 enhances the pro-inflammatory state and anti-tumor activity of human CAR-iMACs in solid tumors.
bioRxiv · Apr 20, 2023 · PreprintImmunology
C. Moore, A. Lei, P. Walsh, O. Trenchevska, G. Saini, T. M. Tarasow, M. Srinivasan, D. Smith, M. P. Greving
This paper introduces a unified peptide array platform for high-resolution antibody epitope binning, mapping, and off-target binding prediction, demonstrating its application with anti-HER2 monoclonal antibodies.
bioRxiv · Jun 22, 2022 · PreprintBioengineering
J. Zhang, J. Hua, W. Wang, M. Liao, N. Li, Y. Zhou, W. Yue, Z. Zhu, Q. Shen, S. Yu, X. Wu, Q. Pan, W. Xu, R. Zhang, X. Wu, , Y. Li
The paper identifies three deeply conserved super-enhancers in placental mammals that are essential for maintaining stem cell pluripotency.
bioRxiv · May 3, 2022 · PreprintCell Biology
H. Yu, Z. Sun, T. Tan, H. Pan, J. Zhao, L. Zhang, J. Chen, A. Lei, Y. Zhu, L. Chen, Y. Xu, M. Chen, S. Gao, G. Q. Daley, J. Zhang
This study shows that disrupting rRNA biogenesis in mouse embryonic stem cells induces a 2C-like state through reorganization of peri-nucleolar heterochromatin and activation of the 2C program.
bioRxiv · Aug 4, 2021Cell Biology
K. R. Breit, C. Rodriguez, A. Lei, S. Hussain, J. D. Thomas
This study examines the effects of prenatal alcohol and THC e-cigarette exposure on motor development in rats, finding delayed sensorimotor development from THC alone and hyperactivity from combined exposure.
bioRxiv · May 26, 2021 · PreprintPharmacology & Toxicology
Z. Zhu, X. Wu, Q. Li, J. Zhang, S. Yu, Q. Shen, Z. Zhou, Q. Pan, W. Yue, D. Qin, Y. Zhang, W. Zhao, R. Zhang, S. Peng, N. Li, , x. chen
The paper shows that KDM3A and KDM3B, along with OCT4/SOX2, regulate H3K9 methylation to maintain pluripotency in porcine-induced pluripotent stem cells.
bioRxiv · Aug 16, 2020Cell Biology
K. R. Breit, C. G. Rodriguez, A. Lei, J. D. Thomas
This study examines the effects of combined THC and alcohol vapor exposure in pregnant rats, finding altered drug metabolism and developmental impacts on offspring.
bioRxiv · Jul 24, 2020Pharmacology & Toxicology
L. Zhang, L. Tian, X. Dai, H. Yu, J. Wang, A. Lei, W. Zhao, Y. Zhu, Z. Sun, H. Zhang, G. Church, H. Huang, Q. Weng, J. Zhang
The paper develops CAR-expressing iPSC-derived macrophage cells with antigen-dependent anti-cancer functions effective against both liquid and solid tumors.
bioRxiv · Mar 28, 2020 · PreprintCell Biology