Author

X. Pei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 2 Microbiology· 2 Biophysics· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:human· 6 Approach:statistical model· 6 Research Focus:cancer & tumor microenvironment· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3

Frequent Co-Authors

X. Wang· 3 shared Y. Chen· 3 shared B. Zhu· 2 shared H. Zhang· 2 shared K. Fan· 2 shared K. Wang· 2 shared L. Cao· 2 shared L. Wang· 2 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

X. Wang

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Author profile →

11 papers

Recent·Most cited

YTHDF2 upregulation and relocation dictate CD8 T cell polyfunctionality in tumor immunity

H. Zhang, X. Luo, W. Yang, Z. Wu, Z. Zhao, X. Pei, X. Zhang, C. Chen, J. H. Lei, Q. Shi, Q. Zhao, Y. Chen, W. Wu, Z. Zeng, H.-Q. Ju, , J. Hou

This paper shows YTHDF2 upregulation and nuclear relocation enhance CD8 T cell polyfunctionality and tumor immunity by regulating gene transcription and mitochondrial fitness.

bioRxiv · Jul 11, 2024 · PreprintImmunology

APOBEC3 mutagenesis drives therapy resistance in breast cancer

A. Gupta, A. Gazzo, P. Selenica, A. Safonov, F. Pareja, E. M. da Silva, D. N. Brown, Y. Zhu, J. Patel, J. Blanco-Heredia, B. Stefanovska, M. A. Carpenter, X. Pei, D. Frosina, A. A. Jungbluth, , S. Chandarlapaty

This study identifies APOBEC3 mutagenesis as a common driver of therapy resistance in breast cancer, associated with poorer clinical outcomes.

bioRxiv · Apr 29, 2024Cancer Biology

A drought stress-responsive metabolite malate modulates stomatal responses through G-protein-dependent pathway in grapevine and Arabidopsis

Y. Mimata, R. Gong, X. Pei, G. Qin, W. Ye

bioRxiv · Apr 2, 2024Plant Biology

EI24-RTRAF interaction represses Nox4 translation, vital for redox balance and insulin production

X. Pei, Z. Wang, W. He, S. Li, Y. Lan, L. Yuan, P. Xu

The paper identifies EI24-RTRAF interaction as a regulator of Nox4 translation, maintaining redox balance and insulin production in pancreatic beta cells.

bioRxiv · Jan 2, 2024Cell Biology

GATA3 ZnF2-defective mutant condensation underlies type I IFN-activating in breast cancer

Y. Chen, Y. Wan, X. Pei, T. Wang, Z. Ma, L. Chen

This study shows that ZnF2-defective GATA3 mutations impair LLPS and DNA binding, reducing breast cancer progression and enhancing type I IFN signaling.

bioRxiv · May 2, 2023 · PreprintCancer Biology

Decoding human in vitro terminal erythropoiesis originating from umbilical cord blood mononuclear cells and pluripotent stem cells

X. Wang, W. Zhang, S. Zhao, H. Yan, Z. Xin, T. Cui, R. Zang, L. Zhao, H. Wang, J. Zhou, X. Li, W. Yue, J. Xi, Z. Zhang, X. Fang, X. Pei

This study maps ex vivo terminal erythropoiesis from umbilical cord blood mononuclear cells and pluripotent stem cells, identifying differences in regulatory dynamics and CD99 expression affecting erythroid expansion and maturation.

bioRxiv · Apr 20, 2023 · PreprintCell Biology

Disulfiram Exerts anti-pulmonary Fibrosis Effect by Activating PGE2 Synthesis

X. Pei, F. Zheng, Y. Li, Z. Lin, Y. Zhang, X. Han, Y. Feng, F. Li, J. Yang, T. Li, Z. Tian, K. Cao, D. Ren, C. Li

This study shows that Disulfiram reduces pulmonary fibrosis by reactivating COX-2-mediated PGE2 synthesis in both cell and animal models.

bioRxiv · Apr 16, 2023 · PreprintCell Biology

Structural and functional characterizations of altered infectivity and immune evasion of SARS-CoV-2 Omicron variant

Z. Cui, P. Liu, N. Wang, L. Wang, K. Fan, Q. Zhu, K. Wang, R. Chen, R. Feng, Z. Jia, M. Yang, B. Zhu, W. Fu, T. Chu, L. Feng, , X. Wang

The paper characterizes structural and functional changes in the SARS-CoV-2 Omicron variant's Spike protein, identifying new immune escape sites and providing insights for vaccine development.

bioRxiv · Dec 29, 2021 · PreprintBiophysics

A subset of Memory B-derived antibody repertoire from 3-dose vaccinees is ultrapotent against diverse and highly transmissible SARS-CoV-2 variants, including Omicron

K. Wang, Z. Jia, L. Bao, L. Wang, L. Cao, H. Chi, Y. Hu, Q. Li, Y. Jiang, Q. Zhu, Y. Deng, P. Liu, N. Wang, L. Wang, M. Liu, , X. Wang

Antibodies from 3-dose vaccinated individuals neutralize Omicron and other variants, with some being ultrapotent and broadly reactive.

bioRxiv · Dec 24, 2021Microbiology

Long noncoding RNAs sustain high expression of exogenous Oct4 by sponging miRNA during reprogramming

Q. Kong, X. Zhang, J. Zhang, K. Zheng, H. Zhang, X. Pei, Z. Yin, D. Wen, Z. Liu

The paper shows lncRNAs and circRNAs sponge miRNAs to maintain Oct4 expression during reprogramming, enhancing reprogramming efficiency.

bioRxiv · Apr 17, 2019 · PreprintCell Biology

Recent mixing of Vibrio parahaemolyticus populations

C. Yang, X. Pei, Y. Wu, L. Yan, Y. Yan, Y. Song, N. Coyle, J. Martinez-Urtaza, C. Quince, Q. Hu, M. Jiang, E. Feil, D. Yang, Y. Song, D. Zhou, , Y. Cui

The paper analyzes genomic data from 1,103 Vibrio parahaemolyticus isolates to show recent genetic mixing among four populations due to increased human-mediated dispersal.

bioRxiv · Jan 19, 2019Microbiology