Author

Z. Sha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. Jiang· 2 shared D. Kunec· 2 shared H. Wu· 2 shared J. Trimpert· 2 shared X. Lin· 2 shared Y. Xiong· 2 shared Z. Zhu· 2 shared B. Fu· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersEvolutionary Biology

C. Jiang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NSP4 mutation T492I drives rapid evolution of SARS-CoV-2 toward Omicron

X. Lin, Z. Sha, C. Zhang, J. M. Adler, R. M. Vidal, C. Langner, B. Fu, Y. Xiong, M. Tan, C. Jiang, H. Zeng, X. Zhang, Q. Li, J. Yan, X. Lu, , Z. Zhu

This study shows that the NSP4 T492I mutation increases SARS-CoV-2 mutation rates and accelerates the emergence of Omicron-like mutations.

bioRxiv · Jul 5, 2024 · PreprintEvolutionary Biology

SHP-1 interacts with NFκB1 to inhibit its phosphorylation and nuclear translocation to suppress excessive bacterial inflammation

N. Wang, S. Tan, M. Wang, H. Liu, S. Han, Z. Wu, J. Ma, S. Chen, Z. Sha

This study shows SHP-1 interacts with NFκB1 to inhibit its phosphorylation and nuclear translocation, thereby suppressing bacterial inflammation in Chinese tongue sole.

bioRxiv · Apr 13, 2024 · PreprintImmunology

T492I mutation alters SARS-CoV-2 properties via modulating viral non-structural proteins

X. Lin, Z. Sha, J. Trimpert, D. Kunec, C. Jiang, Y. Xiong, B. Xu, Z. Zhu, W. Xue, H. Wu

The paper investigates the T492I mutation in SARS-CoV-2 NSP4, showing it increases transmissibility, replication, and antibody evasion by enhancing NSP5 cleavage efficiency and reducing viral RNA-associated chemokines.

bioRxiv · Jan 15, 2023 · PreprintMicrobiology

Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a potential therapeutic target in YAP/TAZ-active cancers

Y. Gu, Y. Wang, Z. Sha, C. He, F. Lan, F.-x. Yu

bioRxiv · Feb 28, 2022Cancer Biology