synaptic & neural circuits

This paper introduces a reward-based social learning paradigm in rats where observers learn visuomotor tasks by watching demonstrators, outperforming controls on task metrics.

This study uses computational fluid dynamics to compare turbulence and blood washout in a healthy heart and a mitral regurgitation patient, highlighting increased turbulence and hemolysis risk in the latter.

This paper presents a unified mechanism for low-energy antifibrillation pacing (LEAP) in cardiac tissue, showing that success depends on refractory boundary length and the exponential decay of success probability with this length.

This paper introduces a framework combining integrated population models and individual-based models to project population dynamics of recolonizing species, showing gray wolves in Washington State will likely colonize all recovery regions by 2030.

The paper reports cryo-EM structures of human pre-60S particles, revealing mechanisms of ribosome assembly involving protein interaction hubs and RNA processing.

This study examines how Aβ42 oligomers alter neuronal network connectivity and dynamics using multielectrode arrays and graph theory analysis in vitro.

This paper studies how fireflies synchronize their flashing in swarms and proposes a mathematical framework to explain the emergence of periodicity without fitting parameters.

This study compares phase separation in 3D and 2D systems using mesoscopic simulations of PSD proteins, showing distinct behaviors in membrane-bound versus cytosolic environments.

This paper describes the creation of DNA-based contractile rings that can contract through two mechanisms, expanding DNA nanotechnology applications.

This study combines fMRI and reinforcement learning to show that the VMPFC encodes a task-wide confidence signal influenced by valence, distinct from dorsal prefrontal networks.

The paper presents a framework using artificial neural networks and genetic algorithms to study spatial decision-making in agents learning to explore an environment without leaving its boundaries.

This study reprograms wound-resident cells in adult mice to generate skin with hair follicles, demonstrating de novo appendage formation.

This paper introduces a 3D confinement method to prime T cell-MHC immune synapses, achieving faster T cell expansion compared to conventional methods.

This study uses a photoswitch to optically modulate electrical activity and contractility in human induced pluripotent stem cell-derived cardiomyocytes.

The paper shows that RNA folds into native structures in protocell models, and this is enhanced by covalent modifications, suggesting a role in early life processes.

This paper develops a convolutional-recurrent neural network to approximate diffusion tractography from T1-weighted MRI, showing results comparable to traditional dMRI tractography.

The paper explains outer hair cell receptor potentials in the mammalian cochlea using a two-degrees-of-freedom model that accounts for local resonance between the cochlear partition and tectorial membrane.

This study shows sympatry promotes convergence in swallowtail butterfly wing color patterns, with stronger effects on females, highlighting ecological interactions' role in trait diversification.

This study shows that the SNX17-Retriever pathway regulates synaptic function and plasticity by maintaining excitatory synapses and enabling structural changes during long-term potentiation.

The paper uses a deep learning system to analyze mouse behavior toward nutritive and nonnutritive sugar, finding distinct behavioral responses before licking.

This study compares in vivo 4D-Flow MRI and FSI simulations in patients with aortic coarctation to assess their agreement in quantifying hemodynamics.

This paper develops a cognitive model to explain how zebrafish make movement decisions in groups, showing it can explain spatial distributions and critical bifurcations in their behavior.

This study shows that dual orexin receptor antagonism reduces attentional impairments caused by NMDA receptor hypofunction in a rat model of schizophrenia.

This study shows that older adults have reduced persistent inward currents and common synaptic inputs in vastus lateralis motor units, contributing to lower strength and poorer force control.

The paper characterizes physiological artefacts in brainstem implants and discusses their implications for closed-loop neuromodulation algorithms.

Mesotrode enables chronic simultaneous mesoscale cortical imaging and subcortical/nerve spiking activity recording in mice, revealing functional connectivity and behavior-related neural networks.

The paper shows that V0d inhibits V0c interactions with complexin and SNAREs, reducing neurotransmission in neurons.

This paper presents a compact rabbit AVN model with dual pathways that replicates normal and pathological rhythms and validates against experimental data.

This study shows that simultaneous knockout of Oxtr and Avpr1b in hippocampal CA2 impairs social memory, with specific deficits in habituation and discrimination tasks.

This study investigates how the weakly electric fish Eigenmannia virescens adapts to destabilizing dynamics through sensorimotor retuning, finding improved tracking performance, reduced sensitivity to disturbances, and enhanced stability.