Identification of Cross-Reactive CD8+ T Cell Receptors with High Functional Avidity to a SARS-CoV-2 Immunodominant Epitope and Its Natural Mutant Variants
C. Hu, M. Shen, X. Han, Q. Chen, L. Li, S. Chen, J. Zhang, F. Gao, W. Wang, Y. Wang, T. Li, S. Li, J. Huang, J. Wang, J. Zhu, , A. Jin
The paper identifies cross-reactive CD8+ T cell receptors with high functional avidity to a SARS-CoV-2 epitope and its variants, showing their ability to activate and kill infected cells.
bioRxiv · Nov 2, 2020Immunology