Author

G. Zhan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

J. Lu· 2 shared B. Gao· 1 shared B. Li· 1 shared C. Wang· 1 shared G. Li· 1 shared H. Bai· 1 shared H. Deng· 1 shared H. He· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. Lu

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2 papers

Recent·Most cited

Harringtonine has the effects of double blocking SARS-CoV-2 membrane fusion

S. Hu, N. Wang, S. Chen, Q. Ding, C. Wang, W. Ma, X. Zhang, Y. Wu, Y. Lv, Z. Xue, H. Bai, S. Ge, H. He, W. Lu, T. Zhang, , L. He

This study shows Harringtonine inhibits SARS-CoV-2 membrane fusion by targeting both the viral S protein and host TMPRSS2, effectively blocking infection in delta and Omicron variants.

bioRxiv · Jan 22, 2022 · PreprintPharmacology & Toxicology

Phase separation of RNA-binding protein promotes polymerase engagement and transcription

W. Shao, X. Bi, B. Gao, J. Wu, Y. Pan, Y. Yin, Z. Liu, W. Zhang, X. Jiang, W. Ren, Y. Xu, Z. Wu, K. Wang, G. Zhan, J. Lu, , X. Shen

The paper investigates how RNA-binding proteins (RBPs) influence RNA polymerase II activity through phase separation, showing that RBPs like PSPC1 enhance polymerase engagement and transcription.

bioRxiv · Mar 26, 2021 · PreprintBiochemistry