S. Ge

SASH1 impairs melanin synthesis and metastasis by down-regulating the TGF-β signaling pathway

This study shows SASH1 reduces melanin synthesis and metastasis by suppressing TGF-β1 signaling through regulation of THBS1 in melanocytes.

Five-layered robot (F-robot) based on functionally graded multilayer foam antiviral low-carbon (F-MAX) system for Pathogenic Microorganism Elimination

The paper introduces an air filtration system using a multilayer composite with antiviral and antibacterial properties, suitable for both commercial and residential environments.

Forces driving transposable element load variation during Arabidopsis range expansion

This study examines TE load variation in Arabidopsis during range expansion, finding increased TE load with expansion and identifying effective population size and transposition rates as key factors.

Intranasal delivery of NS1-deleted influenza virus vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response

This study evaluates an intranasal influenza-based vaccine against SARS-CoV-2 variants, showing it reduces inflammatory response and tissue damage through local immunity.

Boreal Forest Height Mapping using Sentinel-1 Time Series and improved LSTM model

This paper develops an improved LSTM model for predicting boreal forest height using Sentinel-1 time series, achieving better accuracy than existing methods.

Harringtonine has the effects of double blocking SARS-CoV-2 membrane fusion

This study shows Harringtonine inhibits SARS-CoV-2 membrane fusion by targeting both the viral S protein and host TMPRSS2, effectively blocking infection in delta and Omicron variants.

In situ control of root-bacteria interactions using optical trapping in transparent soil

This study uses optical trapping to guide bacteria to specific root cell types and quantify bacterial detachment rates on root surfaces.

Using hypertemporal Sentinel-1 data to predict forest growing stock volume

This study uses Sentinel-1 SAR data to predict forest growing stock volume, showing improved accuracy with more images and specific seasonal image combinations.

Developmental and MAPK-responsive transcription factors drive distinct malignant subtypes and genetic dependencies in pancreatic cancer

The paper identifies three developmental lineages in pancreatic cancer driven by master regulators and shows their association with MAPK activity and therapeutic vulnerabilities.

Robust neutralization assay based on SARS-CoV-2 S-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressed BHK21 cells

This paper develops a robust neutralization assay using SARS-CoV-2 S-bearing VSV pseudovirus and ACE2-overexpressed BHK21 cells to screen antibodies and quantify neutralizing titers.

Virus-free and live-cell visualizing SARS-CoV-2 cell entry for studies of neutralizing antibodies and compound inhibitors

This study develops a virus-free live-cell visualization system for SARS-CoV-2 entry using a fluorescent spike trimer probe, enabling analysis of neutralizing antibodies and inhibitors.

Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike pseudotyped virus

This study investigates whether chloroquine and hydroxychloroquine inhibit 2019-nCoV infection by blocking ACE2 binding, showing both drugs suppress virus entry into ACE2-expressing cells.

Room-temperature-storable PCR Mixes for SARS-CoV-2 Detection

This paper develops freeze-dried PCR mixes for SARS-CoV-2 detection that can be stored at room temperature, maintaining sensitivity and specificity for up to 28 days.

Recent origin of an XX/XY sex-determination system in the ancient plant lineage Ginkgo biloba

The paper resolves the sex-determination system in Ginkgo biloba, identifying XY chromosomes and five potential sex-determination genes originating ~14 million years ago.