X. Bi

Wide-field bond-selective fluorescence imaging: from single-molecule to cellular imaging beyond video-rate

This paper introduces WF-BonFIRE, a wide-field bond-selective fluorescence imaging technique that achieves single-molecule sensitivity and kilohertz speeds for live-cell and bacterial imaging.

Global Marine Cold Seep Metagenomes Reveal Diversity of Taxonomy, Metabolic Function, and Natural Products

The paper analyzes metagenomes from cold seeps to create a database showing microbial diversity and potential natural products.

Rationale design of unrestricted pRN1 derivatives and their application in construction of a dual plasmid vector system for Saccharolobus islandicus

The paper designs mutated pRN1 plasmid backbones to evade CRISPR immunity in Saccharolobus islandicus, enabling stable plasmid vectors and a dual plasmid system for genetic studies.

The origin, divergence and inter-subspecies hybridization of house mice (Mus musculus)

This study traces the origin, divergence, and hybridization of three house mouse subspecies using population genomic data, revealing divergence times and patterns of introgression across Eurasia.

Stability of SARS-CoV-2 in cold-chain transportation environments and the efficacy of disinfection measures

This study investigates how cold-chain conditions and disinfection methods affect SARS-CoV-2 stability, finding that low temperature and seawater increase viral survival while LED light and airflow reduce it.

EgGLUT1 is crucial for the viability of larvae of Echinococcus granulosus sensus lato by involving its glucose uptake

This study identifies EgGLUT1 as a critical gene for glucose uptake in Echinococcus granulosus s.l. larvae, showing that inhibiting it reduces parasite viability and cyst formation in mice.

Phase separation of RNA-binding protein promotes polymerase engagement and transcription

The paper investigates how RNA-binding proteins (RBPs) influence RNA polymerase II activity through phase separation, showing that RBPs like PSPC1 enhance polymerase engagement and transcription.

Rapidly cycling stem cells regenerate the intestine independent of Lgr5high cells

This study identifies Msi1+ cells as rapidly cycling intestinal stem cells that regenerate the intestine independently of Lgr5high cells.

MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure

The paper identifies MISTERMINATE as a mechanism linking mitochondrial dysfunction to proteostasis failure through translational termination impairment and C-terminal extension of mitochondrial proteins.