SMPD3 suppresses IDH mutant tumor growth via dual autocrine-paracrine roles
A. Balakrishnan, F. Saleh, L. Adnani, V. Chinchalongporn, A. El-Sehemy, T. Olender, M. J. Chen, S. T. Ahmad, O. Prokopchuk, L. Vasan, Y. Touahri, R. Islam, S. Sujanthan, D. Zinyk, L. C. Comanita, , C. Schuurmans
This study shows SMPD3 suppresses IDH mutant glioma growth through autocrine and paracrine mechanisms, with higher SMPD3 linked to longer survival in patients.
bioRxiv · Jul 14, 2020 · PreprintCancer Biology