Author

X. Chao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Animal Behavior & Cognition· 1 Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Organism:human· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

B. Wang· 2 shared C. Dong· 2 shared C. Zhang· 2 shared H. Li· 2 shared W.-X. Ding· 2 shared A. Abe· 1 shared A. Hunger· 1 shared A. L. Frazier· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

B. Wang

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Late-Life Alcohol Exposure Does Not Exacerbate Age-Dependent Reductions in Mouse Spatial Memory and Brain TFEB Activity

H. Chen, K. Hinz, C. Zhang, Y. Rodriguez, S. N. Williams, M. Niu, X. Ma, X. Chao, A. L. Frazier, K. E. McCarson, X. Wang, Z. Peng, W. Liu, H.-M. Ni, J. Zhang, , W.-X. Ding

This study examines the effects of late-life alcohol exposure on spatial memory and TFEB activity in young and aged mice, finding that aging has a greater impact than alcohol.

bioRxiv · Feb 23, 2024Animal Behavior & Cognition

Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15

J. Davidson, R. Jain, T. Kizzar, G. Geoghegan, D. J. Nesbitt, A. T. Cavanagh, A. Abe, A. Hunger, X. Chao, I. James, D. Baldwin, R. Verma, K. L. Schueler, V. Hinkoka-Galcheva, S. Michorowska, , J. Simcox

The paper identifies TFEB regulation of BMP lipid catabolism via Pla2g15, showing increased BMP lipids in Pla2g15 knockout mice and cold intolerance upon TFEB knockdown.

bioRxiv · Nov 3, 2023Biochemistry

Autoantibodies against eukaryotic translation elongation factor 1 delta (EEF1D) in two patients with autoimmune cerebellar ataxia

L. Guo, H. Ren, S. Fan, X. Chao, M. Liu, H. Guan, J. Wang

This study identifies anti-EEF1D autoantibodies in two patients with autoimmune cerebellar ataxia, suggesting their potential as a biomarker for diagnosis and recurrence prevention.

bioRxiv · Sep 5, 2023Immunology

The GxcM-Fbp17/RacC-WASP signaling cascade regulates polarized cortex assembly in migrating cells

D. Li, Y. Yang, Y. Wang, X. Chao, J. Huang, S. P. Singh, C. Zhang, J. Lou, P. Gao, S. Huang, H. Cai

This study identifies a signaling cascade involving GxcM, Fbp17, RacC, and WASP that regulates rear cortical actin assembly in migrating Dictyostelium cells.

bioRxiv · Nov 14, 2022 · PreprintCell Biology

Knockdown of DGKZ induces apoptosis and G2/M phase arrest in human acute myeloid leukemia HL-60 cells

X. Chao, C. Dong, H. Li, Y. Tian, X. Li, B. Wang, D. Zhai, Y. Bai

This study shows that knocking down DGKZ in HL-60 cells induces apoptosis and G2/M phase arrest via the caspases pathway.

bioRxiv · Jan 13, 2019Cancer Biology

The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells

X. Chao, G. Wang, Y. Tang, C. Dong, H. Li, B. Wang, J. Wu, J. Zhao

This study investigates how peiminine induces apoptosis in HepG2 cells through both extrinsic and intrinsic pathways, showing dose- and time-dependent effects.

bioRxiv · Jul 25, 2018Cancer Biology