A. Song

Vole genomics links determinate and indeterminate growth of teeth

This study identifies dental genes under positive selection in voles with different molar root structures, linking genetic changes to tooth growth patterns.

Endocytosis Inhibitors Block SARS-CoV-2 Pseudoparticle Infection of Mink Lung Epithelium

This study shows that endocytosis inhibitors block SARS-CoV-2 pseudoparticle infection in mink lung cells, while TMPRSS2 inhibitors have little effect.

Imetelstat-Mediated Alterations in Fatty Acid Metabolism To Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid Leukemia

This study identifies ferroptosis as a mechanism by which imetelstat induces therapeutic effects in AML, showing that targeting fatty acid metabolism enhances its efficacy.

Oncogenic drivers dictate immune control of acute myeloid leukemia.

This study shows that specific AML oncogenes influence immune responses and escape mechanisms, with NrasG12D promoting anti-leukemia immunity that can be counteracted by Myc.

Does Vaping Increase the Likelihood of SARS-CoV-2 Infection? Paradoxically Yes and No

This study investigates whether vaping increases SARS-CoV-2 infection in human bronchial epithelial cells, finding that certain e-liquid ingredients enhance infection while others reduce it.

New Insights into How JUUL Electronic Cigarette Aerosols and Aerosol Constituents Affect SARS-CoV-2 Infection of Human Bronchial Epithelial Cells

This study shows that JUUL aerosols and their constituents increase SARS-CoV-2 infection in human bronchial epithelial cells by boosting ACE2 and TMPRSS2 levels.

Branched ubiquitin chain binding and deubiquitination by UCH37 facilitate proteasome clearance of stress-induced inclusions

This study shows UCH37 deubiquitinates branched ubiquitin chains, enhancing proteasome clearance of stress-induced inclusions.

A Chameleonic Macrocyclic Peptide with Drug Delivery Applications

The paper describes a chameleonic macrocyclic peptide, PDP-23, which can adopt different structures and is used to create a cell-penetrating inhibitor of the P-glycoprotein drug efflux pump.

Stoichiometric Analysis of Protein Complexes by Cell Fusion and Single Molecule Imaging

The paper introduces a method to quantify protein complex stoichiometry in live cells by diluting complexes in situ before single-molecule imaging, avoiding artifacts from detergent isolation or low expression levels.

Real-time Continuous Hand Motion Myoelectric Decoding by Automated Data Labeling

This paper introduces an automated data labeling neural network for real-time hand motion prediction from sEMG signals, achieving high accuracy and early response with no need for manual motion labeling.

High-resolution and high-accuracy topographic and transcriptional maps of the nucleosome barrier

The paper maps nucleosome barriers' topography and Pol II dynamics using single-molecule assays and reveals how H2A.Z and uH2B modify barrier height and width, affecting transcription.

Efficient transposon mutagenesis mediated by an IPTG-controlled conditional suicide plasmid

The paper develops IPTG-controlled conditional suicide plasmids for efficient and regulatable transposon mutagenesis in multiple bacterial species.

Conformational ensemble of the human TRPV3 ion channel

The paper presents cryo-EM structures of human TRPV3 in different states to elucidate its sensitization and gating mechanisms.