R. Singh

This study introduces an n-butanol biosynthesis pathway into Rhodopseudomonas palustris TIE-1 to produce biofuel from CO2 using sustainable resources.

This study shows that nuclear plasticity during confined migration increases DNA damage risk by causing membrane kinking and disruption.

The paper sequences and analyzes the complete mitogenome of the Plum-headed parakeet, revealing phylogenetic insights and taxonomic implications for the Psittacula genus.

The paper develops a high-content screening platform to analyze schistosomiasis drug responses and identifies new bioactive compounds.

This study identifies disulfiram as a novel inhibitor of Mtb's methionine biosynthesis, showing anti-tubercular effects through redox disruption and immune modulation.

This study identifies a nanocompartment in M. tuberculosis containing DypB that enhances resistance to oxidative stress during infection and antibiotic treatment.

This paper designs a thermotolerant, immunogenic SARS-CoV-2 RBD protein fragment that is stable at high temperatures and elicits neutralizing antibodies in guinea pigs.

This study investigates Fe and Mn transport in Rhodopseudomonas palustris TIE-1, showing functional redundancy among transporters and their regulation by Fe and oxygen availability.

This study evaluates diversified agroforestry systems under limited irrigation to improve carbon sequestration, farmer livelihood, and productivity in arid regions.

This study examines the impact of visitor density on stereotypic behaviors in tigers and leopards at a zoo, finding significant associations with visitor numbers but not ambient noise.

This study investigates the potential rediscovery of the Himalayan Quail and identifies factors contributing to its decline, concluding that past efforts have been ineffective and suggesting new methods for future searches.

This study examines how developmental and ambient temperatures affect life-history traits and mating calls in Acanthogryllus asiaticus field crickets, finding temperature-induced changes in body size, lifespan, and call characteristics.

This study shows that paternal effects in threespined sticklebacks lead to offspring phenotypes specific to the environmental stimuli experienced by fathers.

The paper identifies DTD2, an archaeal-derived gene, as critical for plant adaptation to land by detoxifying acetaldehyde through NEDAT deacylation.

The paper identifies a rare L184F mutation in HIV-1 Env that destabilizes the trimer apex, leading to escape from broadly neutralizing antibodies targeting the V2 apex.

This paper presents a high-resolution crystal structure of HIV-1 Nef interacting with AP2, revealing how Nef sequesters CD4 for degradation and identifying a dual-function pocket crucial for both MHC recruitment and CD4 binding.

This study identifies HILPDA as a protein that interacts with DGAT1 and enhances lipid storage in hepatocytes by promoting triglyceride synthesis.

The paper identifies viral factors associated with early broadly neutralizing antibody (bnAb) responses in HIV-1-infected infants and suggests implications for polyvalent vaccination strategies.

The paper quantifies morphological and sub-cellular changes in macrophages and trophoblasts during inflammation using advanced microscopy and machine learning to detect inflammation with high accuracy.

Inhibiting the prostaglandin transporter PGT reduces body fat and induces UCP1-independent thermogenesis in mice on a high-fat diet.

The paper develops a Fyn-specific biosensor to visualize localized, pulsatile kinase activity and spatially regulated signaling crosstalk in live cells.

The paper examines the cost of CpG-creating mutations in various human viruses using existing genomic data and finds they are generally costly.

The paper develops a dynamic site-occupancy model to analyze poaching impacts on wildlife in Cambodia, showing increased poacher site occupancy and ungulate extinction.

The paper identifies a long-lived copper-dependent intermediate in an LPMO enzyme and proposes a mechanism involving its formation from a reactive Cu(III) intermediate during cellulose oxidation.

This paper identifies an acidic cluster motif in SERINC5 that mediates resistance to HIV-1 Nef antagonism, showing its importance in Nef sensitivity without affecting intrinsic antiviral activity.

This study shows that HILPDA deficiency reduces lipid storage in adipose tissue macrophages without affecting inflammation or metabolic issues in obese mice.

This study compares viral characteristics in two HIV-1C infected monozygotic twins with differing elite neutralizing antibody profiles, identifying viral mutations associated with neutralization resistance and susceptibility.

The paper identifies that phosphoserine acidic cluster motifs in transmembrane proteins bind distinct basic regions on clathrin adaptor protein μ subunits, revealing potential for virus-specific inhibition.

The paper investigates chitosan perception in Arabidopsis, showing that fully deacetylated chitosans do not trigger defense responses, while partially acetylated ones do, requiring AtCERK1 and leading to a new receptor model.