T. Wang

This study characterizes the functional roles of IL-15L in rainbow trout, revealing shared and distinct functions compared to IL-2 and IL-15, and provides insights into cytokine family evolution.

This study shows protrusion-localized RNAs are translated in both extending and retracting protrusions, but become silenced and cluster in retracting protrusions.

This study uses a microfluidic Tumor-Vasculature-on-a-Chip model and numerical simulations to investigate how tumor size and positioning affect drug concentration distribution in the tumor microenvironment.

This study identifies two Y chromosome-encoded genes, SyGI and FrBy, that independently determine sex in kiwifruit, revealing a two-factor sex determination system and providing insights for breeding.

This study identifies early urine proteome changes in a bone cancer rat model, detecting significant protein alterations before CT-identified lesions.

This study evaluates genomic data's ability to characterize local adaptation in lodgepole pine, finding genomic and climate data are nearly equivalent for describing adaptation in seedling traits.

This paper studies heart development in monitor lizards, showing that their ventricular septa express conserved transcription factors and have functional similarities to mammalian septa.

This study determines the crystal structures of Mycobacterium tuberculosis σH-RNAP and σH-RPo to elucidate the structural basis of ECF σ factor-mediated transcription initiation.

This study shows that cancer cells are hypersensitive to Hsp90 inhibitors due to a shift in cellular quiescence and activity balance, which can be modulated by growth factors and proteostasis challenges.

The paper studies phage infection dynamics in migrating bacterial populations and identifies a phage transition where bacteria shift from outrunning phages to evolving resistance.

This study shows that FACT facilitates nucleosome formation by tethering H2A-H2B and promoting hexasome and nucleosome assembly.

The paper profiles sgRNA activity in E. coli to improve CRISPR/Cas9 efficiency and identifies limitations of existing prediction models.

The paper identifies social behavior and anxiety as key predictors of nicotine self-administration in adolescent rats, with significant sex differences observed.

This paper develops a CRISPRi library for high-throughput functional genomics in E. coli, identifies sgRNA design rules, and validates gene-phenotype associations with high specificity.