Y. Fan

This study shows that increased mistranslation in E. coli enhances heat shock response via RpoS-dependent RpoH activation, protecting against protein misfolding stress.

This paper identifies the role of TYLCV V2 protein in facilitating the nuclear export of V1 protein and viral systemic infection through host exportin and V1-V2 interaction.

The paper shows chronic ER stress releases protease-resistant DAMPs that activate dendritic cells and drive persistent inflammation.

The paper identifies an alternate cell-cycle entry pathway with inverted G1 signaling and a new point of no return, demonstrated through single-cell microscopy in cell lines and mice.

MeshMonk provides a tool for fast and accurate 3D phenotyping of images, validated with facial images and showing high precision in landmark placement.

This study identifies phase transitions in mutualistic communities during invasion, showing how species interactions and niche overlap drive discontinuous changes in community composition.

This study uses whole-genome sequencing of cancer samples to reconstruct the evolutionary history of 39 cancer types, identifying early and late-stage mutational patterns and driver genes.

The paper shows that ATRX mutations and MYCN amplification are mutually exclusive in neuroblastoma and lead to synthetic lethality.

This study identifies BmNPC1 as a critical host receptor for baculovirus infection, showing its interaction with the viral glycoprotein gp64 and role in endosomal fusion.

This study uses a population dynamics model to show that horizontal gene transfer affects microbial community stability and species coexistence by altering gene flux and direction.

This study identifies CPK2 as a catalytic subunit of cAMP-PKA in Magnaporthe oryzae, showing it plays a role in surface sensing and morphogenesis during pathogenesis, with distinct functions from CPKA.

The paper reports the first draft genome sequence of Lomentospora prolificans, assembled using Illumina and Oxford Nanopore reads, resulting in a highly contiguous genome with 8,656 protein-coding genes.