Y. Hong

This study identifies a polybasic domain in aPKC that mediates PM targeting and kinase activity through Par-6 interaction and allosteric regulation.

This study evaluates Ripasudil's effects on pigmentary glaucoma in a porcine model, showing reduced trabecular meshwork stress fibers, restored phagocytosis, and normalized intraocular pressure.

This study identifies SIZ1-mediated SUMOylation of ROS1 as a mechanism enhancing ROS1 stability and promoting active DNA demethylation in Arabidopsis.

This paper establishes a high-throughput cell-based assay pipeline for evaluating DsbA inhibitors as antivirulence therapeutics using Escherichia coli and UPEC.

This study identifies a comprehensive atlas of B-lymphocytes in triple-negative breast cancer using single-cell RNA-sequencing and antigen receptor profiling, revealing their mature characteristics and prognostic significance.

This study shows NAD+ increases antioxidant capacity in PC12 cells through SIRT2, ERK, and Nrf2 pathways under basal conditions.

This study identifies LEM-3/Ankle1 as a nuclease involved in processing meiotic recombination intermediates, promoting non-crossover (NCO) outcomes and resolving erroneous intermediates during meiotic divisions in C. elegans.

This study identifies LEM-3 as a DNA nuclease that resolves chromatin bridges during cytokinesis in C. elegans embryos, highlighting its role in genome integrity.

The paper reports multiple pepper genomes and finds that retroduplication via LTR-retrotransposons drives expansion of disease resistance genes in plants.