Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
M. Rexhepaj, Y.-J. Park, L. Perruzza, D. Asarnow, M. McCallum, K. Culap, C. Saliba, G. Leoni, A. Balmeli, C. Yoshiyama, M. S. Dickinson, J. Quispe, J. T. Brown, M. A. Tortorici, K. R. Sprouse, , D. Veesler
The paper isolates two human monoclonal antibodies that broadly neutralize PDCoV variants and identifies their mechanism of action.
bioRxiv · Mar 27, 2024 · PreprintBiochemistry
J. Lee, C. Stewart, A. Schaefer, E. M. Leaf, Y.-J. Park, D. Asarnow, J. M. Powers, C. Treichel, D. Corti, R. Baric, N. P. King, D. Veesler
This paper develops a stabilization strategy for sarbecovirus fusion machinery vaccines, showing broad reactivity and protection against SARS-CoV-2 variants.
bioRxiv · Dec 12, 2023Biochemistry
B. Dadonaite, J. Brown, T. E. McMahon, A. G. Farrell, D. Asarnow, C. Stewart, J. Logue, B. Murrell, H. Y. Chu, D. Veesler, J. D. Bloom
This study uses deep mutational scanning to assess how mutations in SARS-CoV-2 spike proteins affect ACE2 binding, cell entry, and serum escape, linking these effects to clade growth rates.
bioRxiv · Nov 13, 2023Microbiology
C.-B. Ma, C. Liu, Y.-J. Park, J. Tang, J. Chen, Q. Xiong, J. Lee, C. Stewart, D. Asarnow, J. Brown, M. A. Tortorici, X. Yang, Y.-H. Sun, Y.-M. Chen, X. Yu, , H. Yan
The paper identifies two European bat MERS-related coronaviruses that use ACE2 as their receptor, revealing a distinct binding mode and host tropism determinants.
bioRxiv · Oct 2, 2023Microbiology
M. Gupta, C. M. Azumaya, M. Moritz, S. Pourmal, A. Diallo, G. E. Merz, G. M. Jang, M. Bouhaddou, A. Fossati, A. F. Brilot, D. Diwanji, E. Hernandez, N. Herrera, H. T. Kratochvil, V. L. Lam, , K. I Pawar
The paper uses cryo-EM and AlphaFold2 to determine the structure of SARS-CoV-2 Nsp2, revealing its zinc-binding site and potential interactions with host proteins.
bioRxiv · May 10, 2021 · PreprintBiophysics
E. Palovcak, D. Asarnow, M. G. Campbell, Z. Yu, Y. Cheng
This study shows that convolutional neural networks can enhance SNR and generate contrast in cryo-EM images, improving image processing outcomes.
bioRxiv · Aug 16, 2020Biophysics
B. Wang, D. Asarnow, W.-H. Lee, C.-W. Huang, B. Faust, P. M. L. Ng, E. Z. X. Ngoh, M. Bohn, D. Bulkley, A. Pizzorno, H. C. Tan, C. Y. Lee, R. A. Minhat, O. Terrier, M. K. Soh, , C.-I. Wang
This study identifies a potent SARS-CoV-2 neutralizing antibody, 5A6, that binds bivalently to two RBDs on the spike protein, showing resistance to key mutations.
bioRxiv · Jul 14, 2020 · PreprintMicrobiology
Y. Zhang, D. P. Bulkley, K. J. Roberts, Y. Xin, D. Asarnow, A. Sharma, B. R. Myers, W. Cho, Y. Cheng, P. A. Beachy
This study presents a cryo-EM structure of Patched, revealing its structural similarity to RND transporters and suggesting a role in cholesterol transport.
bioRxiv · Jun 20, 2018Biophysics