K. Baba

Spontaneous cell morphogenesis via self-propelled actin filaments

The paper shows actin filaments move directionally via treadmilling, driving membrane protrusions and cell migration through physical mechanisms.

Mechanical Netrin-1-DCC Coupling Mediates Netrin-1-induced Axonal Haptotaxis

This study shows that netrin-1-induced axonal haptotaxis is mediated by mechanical coupling between netrin-1 and its receptor DCC, facilitated by shootin1a and actin flow.

Conformational switch in the alpha-synuclein C-terminus domain directs its fibril polymorphs

This study identifies a conformational switch in the alpha-synuclein C-terminus domain that determines fibril polymorphs by altering morphology in response to ionic strength and temperature.

Cell Adhesion-Dependent Biphasic Axon Outgrowth Elucidated by Femtosecond Laser Impulse

This study uses femtosecond laser impulses to investigate how adhesion strength affects axon outgrowth, finding biphasic behavior due to the balance between traction force and adhesion strength.

Arf GTPase-Activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor

This study identifies SMAP1 and AGFG2 as ArfGAPs regulating Weibel-Palade body size and von Willebrand factor exocytosis, respectively.

A novel female-specific circadian clock mechanism regulating metabolism

This study identifies a female-specific circadian clock mechanism involving Siah2 that regulates metabolic rhythms and gene expression in the liver.

Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model

The paper evaluates the fitness of baloxavir-resistant influenza A viruses in ferrets, finding reduced within-host fitness for A/H3N2 I38T and lower between-host fitness for A/H1N1pdm09 I38T compared to wild-type viruses.

Visualization of seasonal phosphorus re-translocation, and expression profile of phosphate transporters in a shortened annual cycle system of the deciduous poplar tree

The paper visualizes seasonal phosphorus re-translocation in poplar trees and analyzes phosphate transporter expression in a shortened annual cycle system.

Dopamine 2 receptor signaling controls the daily burst in phagocytic activity in the mouse retinal pigment epithelium

This study shows that dopamine 2 receptor (D2R) is required for the daily burst of phagocytic activity in mouse retinal pigment epithelium (RPE) after light onset, as D2R knockout mice lack this burst and show altered gene expression.

Admistration of Exogenous Melatonin Improves the Diurnal Rhythms of Gut Microbiota in High Fat Diet-Fed Mice

This study shows that exogenous melatonin administration restores diurnal rhythms in gut microbiota and host metabolism in high fat diet-fed mice.