Author

T. Zou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

G. Zhao· 2 shared H. Wang· 2 shared Q. Wang· 2 shared Y. Wang· 2 shared A. D. Cherniack· 1 shared A. Gupta· 1 shared A. Krez· 1 shared A. R. Fishbein· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersCell Biology

G. Zhao

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Human Amniotic Epithelial Cells Promote Chx10-/Pax6+ Muller Glia Subpopulation Reprogramming into Photoreceptor-like Cells

H. Gao, Z. Yin, X. Huang, Y. Zeng, T. Zou, L. A, C. Zhe, X. Cheng, L. Ge, J. Kang, X. Lin, H. Gong, J. Xie, X. Fan, H. xu

This study identifies a specific Muller glia subpopulation that can be reprogrammed into photoreceptor-like cells through transplantation of human amniotic epithelial cells.

bioRxiv · Feb 1, 2024 · PreprintCell Biology

Ligand supplementation restores the cancer therapy efficacy of an antirheumatic drug auranofin from serum inactivation

Y. Wang, B. Cao, Q. Wang, X. Fang, J. Wang, A. S. C. Chan, X. Xiong, T. Zou

This study shows that adding thiols to auranofin restores its anticancer activity by modulating albumin-gold binding and enhancing therapeutic efficacy.

bioRxiv · Jan 25, 2024Cancer Biology

Defense mechanism of a bacterial retron supramolecular assembly

Y. Wang, C. Wang, Z. Guan, J. Cao, J. Xu, S. Wang, Y. Cui, Q. Wang, Y. Chen, D. Zhang, M. Sun, P. Tao, T. Zou

The paper identifies a phage-encoded DNA methyltransferase as a trigger for the Ec86 retron system and describes its supramolecular assembly and defense mechanism.

bioRxiv · Aug 16, 2023Microbiology

XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells

T. Zou, M. Zhou, A. Gupta, P. Zhuang, A. R. Fishbein, H. Y. Wei, Z. Zhang, A. D. Cherniack, M. Meyerson

The paper shows that deleting XRN1 activates PKR and kills cancer cells with high interferon expression, suggesting XRN1 as a therapeutic target.

bioRxiv · Aug 1, 2023Cancer Biology

LCP1 Regulates Cell Motility in Chondrosarcoma and Correlates with Metastatic Potential and Poor Patient Outcomes

C. A. Watson, J. T. Martin, M. Nakagawa, N. Guardino, T. Zou, E. Peairs, A. Krez, P. Nadesan, Z. Huang, J. Ou, J. Somarelli, B. Alman, J. D. Visgauss

This study identifies LCP1 as a driver of metastasis and poor prognosis in chondrosarcoma through gene expression analysis and in vitro experiments.

bioRxiv · Jan 31, 2023 · PreprintCancer Biology

Revealing the structure of somatic cell membranes by in situ cryo-electron tomography

C. Liu, Y. Zhou, T. Zou, G. Zhao, J. Zhang, H. Wang, H. Wang

This study uses cryo-electron tomography to reveal the high-resolution 3D structure of 293T cell membranes, showing lipid bilayer thickness and protein distribution.

bioRxiv · Sep 19, 2022 · PreprintCell Biology

The high-resolution structure of cell membranes revealed by in situ cryo-electron tomography

G. Zhao, S. Cheng, Y. Yu, T. Zou, H. Wang, C. Tao, G. Bi, Z. H. Zhou, H. Wang

This study uses cryo-electron tomography to reveal the high-resolution 3D structure of human red blood cell membranes and their protein distribution.

bioRxiv · Dec 3, 2021 · PreprintBiophysics