W. Chen

This study demonstrates that GII.17 virus-like particles (VLPs) can be produced and show protective potency against NoV GII.17 infection by blocking saliva histo-blood group antigen binding.

This study shows that H. pylori-induced adrenomedullin promotes inflammation in gastritis by enhancing IFN-γ-producing T-cell responses through AKT and STAT3 phosphorylation and IL-12 production.

This study uses metagenomic sequencing to identify pathogens in culture-negative infective endocarditis cases, providing antimicrobial resistance profiles without culturing.

This study shows HDA19 influences cortical cell fate in Arabidopsis roots by interacting with SCARECROW, adding new components to cortical cell specification.

The paper curates a database of virus-host receptor interactions and identifies common features of viral receptors, showing their role in cross-species transmission.

The paper re-examines Na/K pump currents, finding that two-directional charge movement currents become uni-directional under high stimulation, suggesting a single-channel configuration.

The paper investigates SAM-SAM domain interactions in Eph receptors and identifies SAMD5 as a new binding partner, explaining disease-related mutations.

The paper identifies type-2 CD8+ T cells (Tc2) enriched in severe eosinophilic asthma and shows PGD2 and LTE4 drive their recruitment and activation, contributing to eosinophilia.

The paper measures liver T1rho relaxation times in women and men across different ages and menstrual phases, finding age-dependent decreases in women but not men, and no BMI association.

This study uses molecular dynamics simulations to analyze CDK8/CycC conformational flexibility and ligand binding, identifying key interactions that could inform drug discovery.

This study shows that rapid DNA replication origin licensing in pluripotent stem cells maintains pluripotency by enabling fast MCM loading despite short G1 phases.

This study uses IVIM parameters to differentiate early-stage hepatitis-B fibrotic livers from healthy livers with high accuracy.