Author

Y.-L. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 2 Cancer Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:non-human primate· 2

Frequent Co-Authors

C.-C. Liao· 2 shared C.-P. Sun· 2 shared J.-T. Jan· 2 shared Y.-C. Wang· 2 shared Y.-S. Lin· 2 shared A. Bukreyev· 1 shared A. Findley· 1 shared B. Kuo· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

C.-C. Liao

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

A chloroplast sulfate transporter modulates glutathione-mediated redox cycling to regulate cell division

P.-j. Huang, C.-H. Chen, Y.-L. Lin, H.-Y. Lin, S.-C. Fang

The paper shows that a chloroplast sulfate transporter modulates glutathione levels, which in turn affects cell division in Chlamydomonas reinhardtii.

bioRxiv · Dec 7, 2023 · PreprintCell Biology

MicroRNA-4776-5p acts as a radiosensitizer and predicts the prognosis of patients with head and neck cancer receiving radiotherapy

Y.-L. Lai, C.-C. Wang, Y.-L. Lin, P.-C. Shen, M.-H. Tsai, F.-H. Chen, W.-C. Cheng

The paper identifies miR-4776-5p as a radiosensitizer in head and neck cancer that predicts patient prognosis during radiotherapy.

bioRxiv · Dec 27, 2022 · PreprintCancer Biology

Optogenetic Manipulation of Cell Migration with High Spatiotemporal Resolution Using Lattice Lightsheet Microscopy

W.-C. Tang, Y.-T. Liu, C.-H. Yeh, Y.-L. Lin, Y.-C. Lin, T.-L. Hsu, L. Gao, S.-W. Chang, P. Chen, B.-C. Chen

This study modifies lattice lightsheet microscopy to enable optogenetic manipulation of cell migration with high spatiotemporal resolution, achieving subcellular control and long-term cell viability.

bioRxiv · Jan 2, 2022Cell Biology

Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Syrian hamsters

R. Kulkarni, W.-C. Chen, Y. Lee, C.-F. Kao, S.-L. Hu, H.-H. Ma, J.-T. Jan, C.-C. Liao, J.-J. Liang, H.-Y. Ko, C.-P. Sun, Y.-S. Lin, Y.-C. Wang, S.-C. Wei, Y.-L. Lin, , W. Chang

This study evaluates two vaccinia virus-based SARS-CoV-2 vaccines in mice and hamsters, showing they induce neutralizing antibodies and protect against infection.

bioRxiv · Aug 3, 2021Immunology

A signature of Neanderthal introgression on molecular mechanisms of environmental responses

A. Findley, X. Zhang, C. Boye, Y.-L. Lin, C. Kalita, L. Barreiro, K. E. Lohmueller, R. Pique-Regi, F. Luca

The paper identifies Neanderthal introgression variants that influence gene expression in response to environmental perturbations and validates their regulatory function.

bioRxiv · Mar 15, 2021Evolutionary Biology

CpG-adjuvanted stable prefusion SARS-CoV-2 spike protein protected hamsters from SARS-CoV-2 challenge

C.-E. Lien, Y.-J. Lin, C. Chen, W.-C. Lian, T.-Y. Kuo, J. D. Campbell, P. Traquina, M.-Y. Lin, L. T. C. Liu, Y.-S. Chuang, H.-Y. Ku, C.-C. Liao, Y.-H. Chen, J.-T. Jan, C.-P. Sun, , Y.-L. Lin

This study shows that CpG-adjuvanted S-2P vaccine protected hamsters from SARS-CoV-2 infection by inducing high neutralizing antibodies and reducing viral load.

bioRxiv · Jan 7, 2021Microbiology

A Novel SARS-CoV-2 Multitope Protein/Peptide Vaccine Candidate is Highly Immunogenic and Prevents Lung Infection in an AAV hACE2 Mouse Model and non-human primates

F. Guirakhoo, L. Kuo, J. Peng, J. H. Huang, B. Kuo, F. Lin, Y.-J. Liu, Z. Liu, G. Wu, S. Ding, K.-L. Hou, J. Cheng, V. Yang, H. Jiang, J. Wang, , C. Y. Wang

This paper describes a multitope protein-peptide vaccine candidate, UB-612, that is immunogenic and prevents lung infection in animal models, with ongoing clinical trials.

bioRxiv · Nov 30, 2020 · PreprintImmunology

DDK has a primary role in processing stalled replication forks to initiate downstream checkpoint signaling

N. K. Sasi, F. Coquel, Y.-L. Lin, J. P. MacKeigan, P. Pasero, M. Weinreich

This study identifies DDK's role in processing stalled replication forks to initiate checkpoint signaling and cell cycle arrest.

bioRxiv · Oct 21, 2017Cell Biology