D. Wang

This study reveals that miRNAs directly feedback-regulate their targeting machinery mRNAs, but not upstream biogenesis or downstream effector mRNAs, uncovering segment-specific feedback auto-regulation of the miRNA pathway.

This study identifies and analyzes DNA methyltransferase genes in cotton, showing their functional diversity and stress-specific expression patterns.

This study tests if LAIV affects pneumococcal carriage in humans, finding transient increases in bacterial density but no overall change in acquisition rates.

This study identifies EZH2 as a p53 mRNA-binding protein that enhances translation of gain-of-function p53 mutants, promoting cancer growth and metastasis, and shows that inhibiting EZH2 causes synthetic lethality in these cells.

The paper develops a gene therapy system that uses telomerase activity to kill cancer cells in mice without affecting normal cells.

This study generates transgenic pigs expressing microbial enzymes to enhance feed digestion and reduce nutrient emissions, showing improved growth and lower environmental impact.

The paper analyzes genetic data from Yangtze finless porpoises to show population fragmentation, low genetic diversity, and recent decline linked to habitat degradation and human activity.

The paper studies mutational meltdown in HeLa cancer cell populations, finding high rates of deleterious copy number variations and significant fitness reduction per mutation.

This study identifies SA-mediated suppression of ABA signaling via PP2C phosphatases, revealing a molecular mechanism for hormone crosstalk in plant stress responses.