F. Ren

Structures of PSI-FCPI from Thalassiosira pseudonana in high light provide convergent evolution and light-adaptive strategies in diatom FCPIs

The paper reports cryo-EM structures of PSI-FCPI complexes from Thalassiosira pseudonana under high light, revealing light-adaptive strategies and convergent evolution in diatom FCPIs.

Antibiotics affect the pharmacokinetics of n-butylphthalide in vivo by altering the intestinal microbiota

This study shows antibiotics alter NBP pharmacokinetics in rats by changing intestinal microbiota and reducing CYP3A1 expression.

GABRD promotes the progression of breast cancer through CDK1-dependent cell cycle regulation

This study shows GABRD promotes breast cancer progression by regulating the cell cycle through CDK1 interaction.

Nifuroxazide Suppresses PD-L1 Expression and Enhances the Efficacy of Radiotherapy in Hepatocellular Carcinoma

This study shows nifuroxazide enhances radiotherapy in HCC by reducing PD-L1 expression and improving tumor response.

Conserved Untranslated Regions of Multipartite Viruses: Natural Markers of Novel Viral Genomic Components and Tags of Viral Evolution

This study identifies novel viral genomic components and evolutionary patterns using conserved untranslated regions (UTRs) and UTR-backed iterative BLASTn in multipartite viruses.

SMC1A facilitates gastric cancer cells proliferation, migration and invasion via promoting SNAI2 activated EMT

This study shows SMC1A promotes gastric cancer progression by enhancing SNAI2-driven EMT, suggesting it as a therapeutic target.

Non-Invasive Confocal Fluorescence Imaging of Mice Beyond 1700 nm Using Superconducting Nanowire Single-Photon Detectors

This paper develops a non-invasive imaging technique using NIR-IIc light to image deep tissues in mice, achieving imaging depths of ~800 m and visualizing immune structures in lymph nodes.

Deletion of Letmd1 leads to the disruption of mitochondrial function in brown adipose tissue

This study shows that deleting Letmd1 in mice causes mitochondrial dysfunction in brown adipose tissue, leading to thermogenesis disruption and metabolic disorders.

Cannabidiol Attenuates Pulmonary Arterial Hypertension by Normalizing the Mitochondrial Function in Vascular Smooth Muscle Cells

This study shows that cannabidiol (CBD) reduces pulmonary arterial hypertension by improving mitochondrial function and reducing oxidative stress in vascular smooth muscle cells.

Rapidly cycling stem cells regenerate the intestine independent of Lgr5high cells

This study identifies Msi1+ cells as rapidly cycling intestinal stem cells that regenerate the intestine independently of Lgr5high cells.

Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels

The paper investigates the open conformation and K+ ion conduction mechanism in Kir2.2 channels using a forced open mutation and structural analysis.

Absence of GdX/UBL4A protects against inflammatory bowel diseases by regulating NF-κB signaling in DCs and macrophages