G. Yao

Discrimination of Isomeric Glycans via High-sensitive Engineered Nanopore

This paper designs an engineered nanopore to distinguish isomeric glycans with high sensitivity and achieves over 90% separation accuracy without machine learning.

Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model

This study shows that aucubin promotes functional recovery after spinal cord injury by reducing inflammation and neuronal apoptosis through the TLR4/NF-κB pathway and mitochondrial protection.

Extracellular Fluid Flow Induces Shallow Quiescence through Physical and Biochemical Cues

This study shows that extracellular fluid flow reduces cellular quiescence depth through physical and biochemical cues, making cells more likely to reenter the cell cycle.

DFT and Raman study of all-trans astaxanthin optical isomers

This study uses Raman spectroscopy and DFT calculations to distinguish three optical isomers of all-trans astaxanthin based on differences in Raman band intensities.

Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140

This study identifies SP140 as a druggable epigenetic reader and therapeutic target for Crohn's disease by showing that its inhibition reduces inflammatory macrophage activation and cytokine expression.

Quantifying E2F1 protein dynamics in single cells

This study quantifies E2F1 protein dynamics in single cells using fluorescent reporters, revealing cell cycle-dependent expression patterns and the impact of 3UTR sequences.

Aquaculture potential of Bohai Red and its hybrid with Agropecten irradians concentricus in southern China

This study introduces a new scallop strain, Bohai Red, and evaluates its hybridization with A. irradians concentricus, finding hybrids show improved survival, growth, and heat tolerance.

A lysosomal dimmer switch regulates cellular quiescence depth

This study identifies lysosomal function as a regulator of cellular quiescence depth, showing it acts like a dimmer switch to modulate quiescence and link it to senescence and aging.