Author

L. Sang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cancer & tumor microenvironment· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. Sun· 5 shared J. Shen· 3 shared Q. Hao· 3 shared R. Dong· 2 shared W. Bai· 2 shared X. Wang· 2 shared X. Yao· 2 shared Y. Sun· 2 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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5 shared papersCancer Biology

J. Sun

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

HNF&alpha is a target of the Wnt/beta-catenin pathway and regulates colorectal carcinogenesis

L. Sang, W. Bai, C. Lu, R. Dong, Q. Hao, Y. Zhang, R. Sun, J. Shen, Y. Sun, J. Sun

This study shows HNF4 is upregulated in colorectal cancer and promotes tumorigenesis by being activated by the Wnt/β-catenin pathway.

bioRxiv · Mar 25, 2024 · PreprintCancer Biology

The EGF/EGFR-YAP1/TEAD2 axis-mediated BRAF inhibitor vemurafenib resistance upregulates STIM1 in melanoma

W. Bai, C. Yan, Y. Yang, L. Sang, Q. Hao, X. Yao, J. Yu, Y. Wang, X. Li, M. Meng, J. Yang, J. Shen, Y. Sun, J. Sun

This study identifies the EGF/EGFR-YAP1/TEAD2 axis as a mechanism by which vemurafenib resistance upregulates STIM1 in melanoma.

bioRxiv · Jan 29, 2024 · PreprintCancer Biology

Screening for metastasis-related genes in mouse melanoma cells through sequential tail vein injection

Q. Hao, J. Shen, L. Sang, Y. Bai, j. sun

This study screens for metastasis-related genes in mouse melanoma cells using sequential tail vein injection and identifies differentially expressed genes associated with metastasis.

bioRxiv · Jan 29, 2024Cell Biology

The mitochondrial deoxyguanosine kinase is required for female fertility in mice

Y. Gao, R. Dong, J. Yan, H. Chen, L. Sang, X. Yao, D. Fan, X. Wang, X. Zuo, X. Zhang, S. Yang, Z. Wu, j. sun

This study shows that Dguok knockout causes female infertility in mice by impairing ovarian development, oocyte maturation, and mitochondrial function.

bioRxiv · Nov 12, 2023Cell Biology

O-GlcNAcylation promotes YTHDF1 cytosolic localization and colorectal cancer tumorigenesis

J. Li, M. Ahmad, L. Sang, Y. Zhan, Y. Wang, Y. Yan, Y. Liu, W. Mi, M. Lu, Y. Dai, R. Zhang, M.-Q. Dong, Y. Yang, X. Wang, J. Sun, J. Li

This study shows O-GlcNAcylation of YTHDF1 enhances its cytosolic localization and promotes colorectal cancer by increasing c-Myc expression.

bioRxiv · Nov 21, 2022 · PreprintBiochemistry

Resolving the molecular fingerprint of the distal carboxy tail in modulating CaV1 calcium dependent inactivation

L. Sang, D. C. O. Vieira, D. T. Yue, M. Ben-Johny, I. E. Dick

The paper identifies critical residues in the IQ and ICDI domains that modulate CaV1 channel inactivation through competitive displacement of CaM.

bioRxiv · Jan 6, 2021 · PreprintBiophysics