L. Shi

This study shows that MCL-1 inhibition by BH3 mimetics disrupts mitochondrial dynamics and function in iPSC-derived cardiomyocytes, suggesting a non-apoptotic role for MCL-1 in cardiac health.

This study investigates how terminal tagging affects the oligomerization of the sigma 1 receptor using a modified Western blot protocol, revealing that the N-terminus influences ligand binding effects while the C-terminus is more suitable for modifications.

This study identifies SKI-73 as a CARM1 chemical probe that reduces breast cancer cell invasion by altering epigenetic plasticity, distinct from CARM1 knockout effects.

This study shows that TLR2 stimulation enhances esophageal epithelial barrier function by increasing tight junction protein expression and altering chromatin structure.

This study examines how fungal communities in soil change along a forest disturbance gradient, finding declines in saprotrophic fungi and increases in pathogenic fungi, indicating shifts in soil nutrient limitations.

This study identifies Lsm12 as a regulator that mediates Polη deubiquitination to enhance its recruitment and improve survival under oxidative stress in yeast.

This paper introduces DO-SRS, a method to visualize metabolic dynamics in living tissues by imaging deuterium incorporation into macromolecules.

The paper investigates cytokinesis in C. elegans embryos, showing that positive feedback between myosin and cortical flow accelerates ring constriction rate as the ring shrinks.

This study shows NF45 and NF90 dynamically associate with IEG promoters, regulating their inducible expression through chromatin interactions.

The paper introduces a new method to estimate soil organic carbon stocks by accounting for soil volume changes, revealing an additional carbon sink in global forests.