This study identifies harzianic acid as a multi-target antimicrobial compound effective against Gram-positive bacteria, with resistance linked to specific gene mutations.

bioRxiv · Dec 3, 2021 · PreprintMicrobiology

Time-lapse imaging of bacterial morphology facilitates classification of antimicrobial agents

X. Ouyang, J. Hoeksma, T. K. Siersma, L. W. Hamoen, J. den Hertog

The paper introduces a time-lapse imaging method to classify antimicrobial agents based on their effects on bacterial morphology.

bioRxiv · Sep 8, 2021 · PreprintMicrobiology

In-House Forecasting of Crop Latitude Adaptation through a Daylength-sensing-based Environment Adaptation Simulator (DEAS)

L. Qiu, Q. Wu, X. Wang, G. Zhuang, J. Han, H. Wang, Z. Shang, W. Tian, Z. Chen, Z. Lin, H. He, J. Hu, Q. Lv, J. Ren, J. Xu, , X. Ouyang

This paper introduces DEAS, a simulator that predicts crop latitude adaptation using florigen gene expression, enabling faster breeding for climate-resilient crops.

bioRxiv · Dec 9, 2020Plant Biology

The wheat cytosolic glutamine synthetase GS1.1 modulates N assimilation and spike development by characterizing CRISPR-edited mutants

Y. Wang, W. Teng, Y. Wang, X. Ouyang, X. He, X. Zhao, C. Gao, Y. Tong

This study identifies TaGS1.1 as critical for nitrogen assimilation and spike development in wheat by analyzing CRISPR-edited mutants and their growth responses under varying nitrogen conditions.

bioRxiv · Sep 3, 2020 · PreprintPlant Biology

Integrative Proteomic Analysis of Posttranslational Modification in The Inflammatory Response

F. Ji, M. Zhou, H. Zhu, Z. Jiang, Q. Li, X. Ouyang, Y. Lv, S. Zhang, T. Wu, L. Li

This study integrates proteomic data from human and mouse macrophages to analyze posttranslational modifications in the inflammatory response, identifying PTM crosstalk and novel inflammatory proteins.

bioRxiv · Jul 20, 2020Immunology