Y. Man

Cadmium Disrupts Blood-Testis Barrier (BTB) via An Oxidative Stress-Dependent Autophagy in Prepubertal Rats

This study shows cadmium exposure disrupts blood-testis barrier function in prepubertal rats via oxidative stress-induced autophagy and mTOR2 signaling impairment.

Feeding Rates of Sessile versus Motile Ciliates are Hydrodynamically Equivalent

The paper compares feeding rates of motile and sessile ciliates, finding they are hydrodynamically equivalent in nutrient transport efficiency.

TLR9 activation in large wound induces tissue repair and hair follicle regeneration via gamma delta T cells

This study shows that TLR9 activation in wounds promotes tissue repair and hair follicle regeneration through gamma delta T cells by increasing AREG production and modulating keratinocyte fate.

Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals.

The paper identifies senescent SPP1+ macrophages as inhibitors of immune response and tissue repair in aged mice using ECM scaffolds.

Motion Blur Microscopy

This paper introduces motion blur microscopy to image cell adhesion in whole blood flow without dilution, enabling analysis of adhesion dynamics in physiological conditions.

Spp1 secreted by macrophages impairs osteogenic ability of Ctsk+Fmod+ periosteal cells in jaw bone

The paper identifies a Ctsk+Fmod+ periosteal cell subset in jaw bones that is impaired by Spp1 secreted by macrophages, highlighting a potential target for improving bone grafting.

Evaluating Evasion Strategies in Zebrafish Larvae

This study evaluates evasion strategies in zebrafish larvae, finding that they escape in a direction orthogonal to predator heading to maximize distance.

Catch bonds in sickle cell disease: shear-enhanced adhesion of red blood cells to laminin

This paper investigates catch bonding in sickle cell disease by measuring RBC adhesion dynamics to laminin under shear flow, revealing patient-specific variations in bond strength and clinical relevance.

Integrating Network Pharmacology And Experimental Verification To Explore The Mechanism Of Qionggui Power Against Atherosclerosis

This study uses network pharmacology and in vitro experiments to identify Qionggui Power's active ingredients and mechanisms against atherosclerosis, showing suppression of the NF-κB pathway.

Sickle red blood cell derived extracellular vesicles activate endothelial cells and enhance sickle red cell adhesion mediated by von Willebrand factor

This study shows that sickle RBC-derived extracellular vesicles activate endothelial cells and enhance RBC adhesion via von Willebrand factor, with implications for SCD treatment.

Spatial anchor of adaptive immune cell around biomaterials mediated large-scale wound regeneration

This study shows that adaptive immune cells around biomaterials promote hair follicle regeneration by activating fibroblasts, highlighting their role in wound healing.

The Diameter Factor of Aligned Electrospinning Membranes Facilitates Cutaneous Wound Healing by Promoting Epithelialization

This study shows that aligned electrospinning membranes with 319 nm diameter enhance skin wound healing by promoting epithelialization and macrophage transformation through IL10 and TGFβ expression.

Application of EGCG modified EDC/NHS cross-linked extracellular matrix to promote macrophage adhesion

The paper develops an EGCG-modified EDC/NHS collagen membrane to enhance macrophage adhesion and vascularization, showing improved cell viability and potential for implant dentistry.

Consideration of macrophage phenotypes under biomaterials mediated host defense process

The paper shows that screening macrophages before analysis is crucial for accurate phenotype identification and that CAMP expression does not fit traditional M1/M2 classification.

Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing

This study investigates how different surface topographies of biomaterial scaffolds affect skin wound healing in mice, finding that aligned scaffolds enhance regeneration and modulate immune responses.

ARG1 could be expressed by human, but not represent for repair

This study investigates whether ARG1 is expressed during human bone healing and finds it is not a reliable marker for regeneration.