Author

Y.-Y. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Biophysics· 1 Microbiology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2

Frequent Co-Authors

L.-L. Du· 2 shared X.-M. Liu· 2 shared B. Hu· 1 shared B. Li· 1 shared B. Wang· 1 shared B. Yan· 1 shared B.-Z. Wang· 1 shared C. Liu· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersCell Biology

L.-L. Du

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Transgenic female mice producing trans 10, cis 12-conjugated linoleic acid present excessive prostaglandin E2, adrenaline, corticosterone, glucagon, and FGF21

Y. Rao, L.-W. Liang, M.-J. Li, Y.-Y. Wang, B.-Z. Wang, K.-M. Gou

This study shows that transgenic female mice producing t10c12-CLA exhibit metabolic changes including increased prostaglandin E2, adrenaline, corticosterone, glucagon, and FGF21, indicating systemic hormonal effects.

bioRxiv · Apr 21, 2023 · PreprintPhysiology

Mechanism of glucocorticoid receptor activation regulated expression of thrombospondin-1

G.-X. Zhang, Y.-Y. Wang, Y.-Y. Song, W.-Y. Jiang, H.-T. Zhang, J.-W. Chen, K. Murao, W.-P. Sun

This study shows that glucocorticoid receptor activation increases TSP-1 expression through p38 MAPK and AGO-2 phosphorylation, and microRNA-1-3p inhibition in endothelial cells and platelets.

bioRxiv · Apr 13, 2023 · PreprintPathology

Molecular and structural mechanisms of ZZ domain-mediated cargo recognition by autophagy receptor Nbr1

Y.-Y. Wang, J. Zhang, X.-M. Liu, M.-Q. Dong, K. Ye, L.-L. Du

The paper identifies two new NVT cargos bound by Nbr1-ZZ1 and reveals the structural basis of ZZ domain-mediated cargo recognition in selective autophagy.

bioRxiv · Feb 7, 2021 · PreprintCell Biology

Histone lysine crotonylation regulates cell-fate determination of neural stem/progenitor cells by activating bivalent promoters

C.-M. Liu, S.-K. Dai, P.-P. Liu, H.-Z. Du, X. Liu, Y.-J. Xu, C. Liu, Y.-Y. Wang, Z.-Q. Teng

This study identifies histone lysine crotonylation as an active promoter mark that regulates gene expression and neuronal differentiation in neural stem/progenitor cells.

bioRxiv · May 27, 2020Cell Biology

ICOS enhances follicular T helper responses and deteriorates the pathogenic process of liver in mice infected with Schistosoma japonicum

B. Wang, S. Liang, Y.-Y. Wang, Y. Wang, C.-M. Xia

This study shows that ICOS overexpression in mice worsens liver inflammation and fibrosis in Schistosoma japonicum infection by increasing Tfh cell frequency and altering cytokine responses.

bioRxiv · Feb 27, 2020 · PreprintImmunology

Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin

P. Zhou, X.-L. Yang, X.-G. Wang, B. Hu, L. Zhang, W. Zhang, H.-R. Si, Y. Zhu, B. Li, C.-L. Huang, H.-D. Chen, J. Chen, Y. Luo, H. Guo, R.-D. Jiang, , Z.-L. Shi

This paper identifies and characterizes a novel coronavirus (nCoV-2019) causing a human pneumonia outbreak, showing its close genetic relationship to bat coronaviruses and its use of the ACE2 receptor for cell entry.

Nature · Feb 3, 2020Peer-reviewedMicrobiology

Direct synthesis of EM-visible gold nanoparticles on genetically encoded tags for single-molecule visualization in cells

Z. Jiang, X. Jin, Y. Li, S. Liu, X.-M. Liu, Y.-Y. Wang, P. Zhao, X. Cai, Y. Liu, Y. Tang, X. Sun, Y. Liu, Y. Hu, M. Li, G. Cai, , W. He

This paper develops a method to directly synthesize EM-visible gold nanoparticles on genetically encoded tags for single-molecule visualization in cells, achieving high labeling efficiency in both prokaryotic and eukaryotic cells.

bioRxiv · Jan 17, 2019Biophysics

Antibody-mediated immobilization of virions in mucus

M. Jensen, Y.-Y. Wang, S. Lai, M. G. Forest, S. A. McKinley

This study analyzes virion movement in mucus using single-particle tracking to show how antibodies immobilize virions through cooperative binding and entanglement with mucin.

bioRxiv · Jan 11, 2019Immunology