Z. Xin

Decoding human in vitro terminal erythropoiesis originating from umbilical cord blood mononuclear cells and pluripotent stem cells

This study maps ex vivo terminal erythropoiesis from umbilical cord blood mononuclear cells and pluripotent stem cells, identifying differences in regulatory dynamics and CD99 expression affecting erythroid expansion and maturation.

Avirulent ME49Δgra5 Protecting Hosts Against Toxoplasma gondii Infection and Breast Tumors

This paper shows that the gra5 knockout T. gondii strain ME49Δgra5 is avirulent, prevents cyst formation, and protects against T. gondii infection and breast tumor growth in mice.

IRE-1α is a key switch of pyroptosis and necroptosis in mice by dominating Gasdermin D

This study shows IRE-1α regulates both necroptosis and pyroptosis in mice by modulating GSDMD activity, with implications for therapeutic targeting in tissue injuries.

Oxidative phosphorylation pathway disruption is an alternative pathological mechanism leading to Diamond-Blackfan anemia

This study identifies oxidative phosphorylation pathway disruption as an alternative mechanism causing Diamond-Blackfan anemia and shows coenzyme Q10 can rescue erythroid defects.

Construction of competing endogenous RNA interaction networks as prognostic markers in metastatic melanoma

This study constructs a ceRNA network in metastatic melanoma to identify prognostic markers and therapeutic targets, finding miR-3662 may be used in treatment.

COMPOSITUM 1 (COM1) contributes to the architectural simplification of barley inflorescence via meristem identity signals

This study identifies COM1 as a gene regulating inflorescence shape in barley by controlling meristem identity signals, with implications for evolution and breeding.

Fertility of Pedicellate Spikelets in Sorghum is Controlled by a Jasmonic Acid Regulatory Module

This paper identifies a jasmonic acid regulatory module controlling spikelet fertility in sorghum, showing that mutations in MSD1 and MSD2 increase grain number per panicle.