Author
A. Khan
Agricultural Research Service
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2016-2026 · peak 16/yrCo-Author Collaboration Network
10 top collaborators · 8 mutual co-author links70 papers
Recent·Most cited
- Cancer BiologybioRxivPreprint
RICTOR Drives ZFX-mediated Ganglioside Biosynthesis to Promote Breast Cancer Progression.
K. Rajput, M. N. Ansari, S. K. Jha…·U. Dasgupta
This study identifies RICTOR's role in regulating ganglioside biosynthesis via ZFX and UGCG, promoting breast cancer progression through EGFR signaling.
DOI 10.1101/2022.01.10.475595 - Evolutionary BiologyProceedings of the National Academy of SciencesPeer-reviewed
Genomic evidence for inbreeding depression and purging of deleterious genetic variation in Indian tigers
A. Khan, K. Patel, H. Shukla…·U. Ramakrishnan
This study uses whole-genome sequencing of Indian tigers to show that small-isolated populations have higher inbreeding depression and purging of deleterious alleles compared to larger, connected populations.
DOI 10.1073/pnas.2023018118 - Cell BiologybioRxiv
A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair
S. Lechuga, A. X. Cartagena-Rivera, A. Khan…·A. I. Ivanov
This study identifies UNC-45A as a regulator of intestinal epithelial barrier integrity and repair, showing its role in maintaining junctions and contractile forces.
DOI 10.1096/fj.202200154r - Cancer BiologyCell ReportsPeer-reviewed
Targeting Glioblastoma Signaling and Metabolism with A Re-Purposed Brain-Penetrant Drug
J. Bi, A. Khan, J. Tang…·P. S. Mischel
This study identifies fluoxetine as a potential therapy for glioblastoma by inhibiting SMPD1 and enhancing temozolomide efficacy, with real-world evidence suggesting improved survival.
DOI 10.1016/j.celrep.2021.109957 - ImmunologybioRxiv
PRMT5 in T cells drives Th17 responses, mixed granulocytic inflammation and severe allergic airway inflammation
B. W. Lewis, S. A. Amici, H.-Y. Kim…·M. Guerau-de-Arellano
This study shows PRMT5 in T cells drives Th17 responses and severe allergic airway inflammation in a mouse model of asthma.
DOI 10.4049/jimmunol.2100994 - ImmunologybioRxivPreprint
CD20+ T cells are associated with inflammatory responses in experimental arthritis.
M. A. Pineda, P. Pan, Y. Wang…·M. H. Nyirenda
This study identifies CD20+ T cells as inflammatory contributors in murine arthritis, showing their expansion and cytokine production in lymph nodes and joints.
DOI 10.1101/2021.10.12.464081 - Cancer BiologybioRxiv
Multi-modal profiling of the extracellular matrix of human fallopian tubes and serous tubal Intraepithelial carcinomas
C. Renner, C. Gomez, M. R. Visetsouk…·P. K. Kreeger
The paper characterizes the extracellular matrix (ECM) composition in benign fallopian tubes and serous intraepithelial carcinomas (STICs), identifying ECM protein changes associated with STIC formation.
DOI 10.1369/00221554211061359 - Plant BiologybioRxivPreprint
Sugar Beet Extract Acts as a Natural Bio-Stimulant for Physio-Biochemical analysis of Hordeum Vulgare L. under Induced Salinity Stress
N. A. Shah, S. Ullah, M. N. Khan…·W. M. Khan
This study evaluates sugar beet extract's ability to mitigate salinity stress effects on barley growth and physiological traits.
DOI 10.1101/2021.08.19.457015 - Cell BiologybioRxiv
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis
E. Schiebel, W. Zhang, A. Khan…·T. Soellner
The paper identifies an amphipathic α-helix in Apq12 that regulates NPC biogenesis by modulating Brl1 and Brr6 interactions and phosphatidic acid accumulation at the nuclear envelope.
DOI 10.1098/rsob.210250 - Cancer BiologybioRxivPreprint
DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohorts
S. H. Strand, B. Rivero-Gutierrez, K. E. Houlahan…·K Owzar
The paper develops a classifier for DCIS recurrence using genomic data from two cohorts and identifies pathways and stroma-specific signatures associated with progression to invasive cancer.
DOI 10.1101/2021.06.16.448585 - BiophysicsbioRxiv
Cryptic pathogen-sugar interactions revealed by universal saturation transfer analysis
C. J. Buchanan, B. Gaunt, P. J. Harrison…·B. G. Davis
This paper introduces uSTA, an NMR method to analyze protein-ligand interactions, revealing SARS-CoV-2 spike binds sialoside sugars via the NTD and showing variants-of-concern lose this binding.
DOI 10.1126/science.abm3125 - MicrobiologybioRxiv
Epigallocatechin Gallate from Green Tea Effectively Blocks Infection of SARS-CoV-2 and New Variants by Inhibiting Spike Binding to ACE2 Receptor
J. Liu, B. H. Bodnar, F.-Z. Meng…·W. Ho
This study shows that EGCG from green tea inhibits SARS-CoV-2 and its variants by blocking spike protein binding to ACE2 receptors.
DOI 10.1186/s13578-021-00680-8 - Scientific Communication & EducationNature Human BehaviourPeer-reviewed
Evaluating features of scientific conferences: A call for improvements
S. Sarabipour, B. Schwessinger, F. N. Mumoki…·T. Mestrovic
The paper evaluates features of scientific conferences and identifies areas for improvement, including diversity, inclusivity, and environmental sustainability.
- PhysiologybioRxivPreprint
Whole-body plethysmography revisited
S. Hülsmann, A. Khan, L. Hagos…·C. Dullin
This study revisits whole-body plethysmography by designing an artificial lung model to evaluate its measurements and reliability, revealing that pressure changes are influenced by both airway resistance and air conditioning.
DOI 10.1101/2021.02.24.432470 - Plant BiologybioRxiv
Effect of exogenously applied alpha-tocopherol on vital agronomic, physiological and biochemical attributes of Lentil (Lens culinaris Medik.) under induced drought stress
W. Shah, s. ullah, S. Ali…·M. Ali
This study shows that applying alpha-tocopherol to lentils under drought stress improves growth, physiological, and biochemical traits by reducing oxidative stress and enhancing stress tolerance.
DOI 10.1371/journal.pone.0248200 - Pharmacology & ToxicologybioRxivPreprint
In-silico studies of Neurocognitive and Neuropharmacological effect of Bacopa monnieri (L.)
This study investigates the neurocognitive and neuropharmacological effects of Bacopa monnieri through in-silico methods, finding that its therapeutic properties arise from a combination of phytochemicals rather than a single compound.
DOI 10.1101/2021.01.20.427542 - Plant BiologybioRxiv
Rare instances of haploid inducer DNA in potato dihaploids and ploidy-dependent genome instability
K. R. Amundson, B. Ordonez, M. Santayana…·L. Comai
The paper investigates the mechanism of dihaploid formation in potato by analyzing genome instability and the presence of haploid inducer DNA in dihaploids and hybrids.
DOI 10.1093/plcell/koab100 - ImmunologybioRxivPreprint
Naturally secreted bacterial outer membrane vesicles: potential platform for a vaccine against Campylobacter jejuni
A. Singh, A. Khan, T. Ghosh…·A. I. Mallick
This study demonstrates that chitosan-coated outer membrane vesicles (OMVs) from Campylobacter jejuni induce strong immune responses and reduce cecal colonization in mice, suggesting their potential as a vaccine platform.
DOI 10.1101/2020.10.16.342261 - Cell BiologybioRxivPreprint
Altered glutamine metabolism of cultured fibroblasts predicts severity of cardiac dysfunction in the dilated cardiomyopathy with ataxia syndrome (DCMA), a mitochondrial cardiomyopathy
M. A. King, K. Heger, A. Khan…·I. A. Lewis
The paper identifies altered glutamine and lactate metabolism in DCMA patient fibroblasts as a predictor of cardiac dysfunction severity.
DOI 10.1101/2020.10.11.334938 - ImmunologybioRxivPreprint
Intrarenal B cells integrate in situ innate and adaptive immunity in human renal allograft rejection
Y. Asano, J. Daccache, D. Jain…·M. R. Clark
The paper identifies a unique B cell subset in renal allograft rejection that contributes to local inflammation through self-reactive antibodies and innate-like signaling.
- Plant BiologybioRxiv
Gene Loss and Evolution of the Plastome
T. K. Mohanta, A. Khan, A. Hashem…·A. Al-Harrasi
The paper analyzes 2511 chloroplast genomes to study gene loss, transfer to the nuclear genome, and evolutionary history of chloroplasts across plant lineages.
DOI 10.3390/genes11101133 - MicrobiologymBioPeer-reviewed
In vivo analysis of Trypanosoma cruzi persistence foci at single cell resolution
A. I. Ward, M. D. Lewis, A. Khan…·J. M. Kelly
This study identifies skeletal muscle and skin as major sites of Trypanosoma cruzi persistence in chronic murine infections using high-sensitivity imaging.
- ImmunologybioRxiv
Exaggerated in vivo IL-17 responses discriminate recall responses in active TB
G. Pollara, C. T. Turner, G. S. Tomlinson…·M. Noursadeghi
The paper shows that exaggerated IL-17A/F responses in active TB distinguish it from cured or latent TB, suggesting therapeutic targeting of this pathway.
DOI 10.1126/scitranslmed.abg7673 - Pharmacology & ToxicologybioRxivPreprint
Rapid tolerance to morphine in the myenteric neurons of the small intestine is independent of β-arrestin-2 and mediated by PKC
K. H. Muchhala, J. C. Jacob, I. Alam…·H. I. Akbarali
This study shows that morphine tolerance in the small intestine develops rapidly and is independent of β-arrestin-2 but mediated by PKC, unlike peripheral antinociceptive tolerance.
DOI 10.1101/2020.07.17.209437 - BioengineeringbioRxivPreprint
Biodegradation of polyester polyurethane by Aspergillus flavus G10
D. A. Schaefer, S. Khan, S. Nadir…·J. Xu
This study investigates the biodegradation of polyester polyurethane by Aspergillus flavus G10 using multiple analytical techniques and identifies conditions that enhance degradation.
DOI 10.1101/2020.06.25.170654 - Cell BiologybioRxiv
Emerin regulation of nuclear stiffness is required for fast amoeboid migration in confined environments
S. B. Lavenus, K. W. Vosatka, A. P. Caruso…·J. S. Logue
This study shows that emerin regulates nuclear stiffness, which is essential for fast amoeboid migration of melanoma cells in confined environments.
DOI 10.1242/jcs.259493 - Cell BiologyCanadian Journal of CardiologyPeer-reviewed
Reversible Mitochondrial Fragmentation in iPSC-Derived Cardiomyocytes from Children with DCMA, a Mitochondrial Cardiomyopathy
L. Rohani, P. Machiraju, R. Sabouny…·S. C. Greenway
This study uses iPSC-derived cardiomyocytes from DCMA patients to show reversible mitochondrial fragmentation and OPA1 isoform imbalance, suggesting SS-31 as a potential therapy.
DOI 10.1016/j.cjca.2019.09.021 - ImmunologybioRxiv
Computational vaccinology based development of multi-epitope subunit vaccine for protection against the Norovirus infections
I. Ahmad, S. S. Ali, I. Shah…·D.-Q. Wei
This study develops a multi-epitope subunit vaccine against Norovirus using computational vaccinology, selecting antigenic epitopes and modeling the vaccine structure for potential experimental validation.
DOI 10.1080/07391102.2020.1845799 - ImmunologybioRxiv
Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in Rheumatoid Arthritis.
Y. Wang, A. Khan, A. Antonopoulos…·M. A. Pineda
This study shows that reduced α2-6 sialylation in synovial fibroblasts contributes to a pro-inflammatory phenotype in RA by altering glycosylation pathways.