F. Yu

This study shows that STIM1 phosphorylation at ERK/CDK sites is not required for SOCE, cell migration, or ER partitioning during mitosis.

This study constructs a defined gut bacterial community of 104 strains and investigates strain-strain and strain-nutrient interactions through amino acid dropout experiments.

This study identifies SARS-CoV-2 ORF8 as a protein that downregulates MHC-I to evade immune detection by promoting lysosomal degradation, reducing CTL-mediated cell elimination.

This paper develops ROS-degradable polythioketal urethane foams for skin wound healing, showing improved tissue integration and ECM deposition compared to existing materials.

The paper identifies thousands of novel cancer-specific antigens by analyzing PTMs in immunopeptidomics data from multiple sources and reveals their impact on HLA binding and TCR recognition.

This study evaluates antibody resistance and ACE2 usage in SARS-CoV-2 variants, finding SA501Y.V2 shows the highest resistance and expanded host range.

The paper develops a FRET biosensor using intrinsically disordered proteins to monitor osmotic stress effects across multiple organisms.

This study shows cannabinoids affect food preference and consumption in Drosophila without requiring cannabinoid receptors, with some inhibiting intake and others promoting starvation resistance.

This study identifies structural variants in Brassica oleracea genomes that contribute to morphological divergence between cauliflower and cabbage.

The paper combines epiGBS markers with long-read transcriptome sequencing to assess DNA methylation and transcriptome differentiation in Reynoutria across habitats, finding marginal methylation differentiation and no individual loci associated with habitat.

This study identifies MCAD as a critical enzyme for fatty acid metabolism in GBM, showing its essential role in preventing mitochondrial damage and apoptosis.

This study identifies a Krt5-BMP4 mechanosignaling pathway that regulates histone modifications and blastema cell remodeling during zebrafish heart regeneration.

This study develops a framework to characterize how intrinsically disordered proteins (IDRs) respond to their chemical environment, finding sequence-dependent sensitivity and potential regulatory roles.

The paper characterizes a novel EBV strain, Yu103, associated with both nasopharyngeal carcinoma and B-cell lymphoma, showing its dual tropism and unique genomic features.

This paper identifies Kupffer cell release of platelet activating factor (PAF) as a key driver of nanocarrier toxicity and shows that PAFR inhibition prevents dose-limiting toxicities in mice.

This paper develops MMP13-targeted nanoparticles for RNA interference to treat post-traumatic osteoarthritis, showing significant reduction in MMP13 expression and cartilage damage in mouse models.

The paper curates a database of phage-host receptor interactions and finds that viral receptors, both in phages and mammalian viruses, are central in host protein-protein interaction networks.

This study examines gut microbiome differences between lung cancer patients and healthy individuals, finding altered microbial composition but unclear links to cancer development.

The paper characterizes two E. coli lineages, ST167 and ST617, responsible for carbapenem-resistant infections, revealing their genomic evolution and resistance mechanisms.

This paper reports the structure of HpiC1, a Stig cyclase involved in hapalindole/fischerindole biosynthesis, revealing its dimeric assembly and key residues for catalytic steps.

This paper introduces a microfluidic-based mini-metagenomic method to extract novel microbial genomes from complex environmental samples, revealing 29 new genomes with diverse metabolic pathways and SNP distributions.