Author

Q. Lian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

L. Chen· 3 shared J. Gu· 2 shared W. Guo· 2 shared Y. Zhang· 2 shared A. Vernet· 1 shared A.-c. Meunier· 1 shared B. Yan· 1 shared B. Zheng· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCancer Biology

L. Chen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

HCCDB v2.0: Decompose the Expression Variations by Single-cell RNA-seq and Spatial Transcriptomics in HCC

Z. Jiang, Y. Wu, Y. Miao, K. Deng, F. Yang, S. Xu, Y. Wang, R. You, L. Zhang, Y. Fan, W. Guo, Q. Lian, L. Chen, X. Zhang, Y. Zheng, J. Gu

HCCDB v2.0 integrates bulk, single-cell, and spatial transcriptomic data from HCC samples to enhance meta-analysis and provide new metrics for gene expression patterns.

Genomics, Proteomics & Bioinformatics · Feb 3, 2024Peer-reviewedCancer Biology

Agonistic anti-CD40 converts Tregs into Type 1 effectors within the tumor micro-environment

V. Maltez, C. Arora, R. Sor, Q. Lian, R. H. Vonderheide, R. N. Germain, K. T. Byrne

This study shows that agonistic anti-CD40 converts Tregs into Type 1 effectors in the tumor microenvironment via IL-12 and IFN-γ signaling from dendritic cells.

bioRxiv · Oct 17, 2022 · PreprintImmunology

High-frequency synthetic apomixis in hybrid rice

A. Vernet, D. Meynard, Q. Lian, D. Mieulet, O. Gibert, M. Bissah, R. Rivallan, A.-c. Meunier, K. Shankle, J. Frouin, K. Shankle, I. Khanday, R. Mercier, V. Sundaresan, E. Guiderdoni

This study demonstrates high-frequency synthetic apomixis in hybrid rice by inducing MiMe mutations and BBM1 expression, resulting in over 95% clonal seed production across generations.

bioRxiv · Oct 14, 2022Plant Biology

Comprehensive Analysis of Spatial Architecture in Primary Liver Cancer

R. Wu, W. Guo, X. Qiu, S. Wang, C. Sui, Q. Lian, J. Wu, Y. Shan, Z. Yang, S. Yang, T. Wu, K. Wang, Y. Zhu, S. Wang, C. Liu, , L. Chen

This study constructs high-resolution spatial transcriptomes of primary liver cancers to analyze spatial architecture and identify tumor microenvironment features.

bioRxiv · May 24, 2021Cancer Biology

Mesenchymal stem cells protect retinal ganglion cells from degeneration via mitochondrial donation

D. JIANG, H. Feng, Z. Zhang, B. Yan, L. Chen, C. Ma, C. Li, S. Han, Y. Zhang, P. Chen, H.-F. Tse, Q. Fu, K. Chiu, Q. Lian

This study shows that mesenchymal stem cells (MSCs) protect retinal ganglion cells (RGCs) from degeneration by donating mitochondria, reducing inflammation, and preserving retinal function in a mouse model.

bioRxiv · Aug 19, 2018 · PreprintCell Biology