USP10 strikes down β-catenin by dual-wielding deubiquitinase activity and phase transition potential
Y. Wang, A. Mao, J. Liu, P. Li, S. Zheng, T. Tong, Z. Li, H. Zhang, L. Ma, J. Lin, Z. Pang, Q. Han, F. Li, X. Zhang, M. Chen, , R. Sheng
This study identifies USP10 as a novel regulator of β-catenin through dual mechanisms involving deubiquitination and phase separation, with implications for cancer treatment.
Cell Chemical Biology · Nov 1, 2023Peer-reviewedCell Biology