Author

N. Cui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Evolutionary Biology· 2 Animal Behavior & Cognition· 1 Cell Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:cryo-EM· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

C. Wang· 2 shared F. Lei· 2 shared J.-T. Zhang· 2 shared L. Yang· 2 shared N. Jia· 2 shared X. Chen· 2 shared Y. Xu· 2 shared A. Feldman· 1 shared

Activity by Year

2016-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

C. Wang

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8 papers

Recent·Most cited

Genetic purging of strongly deleterious mutations underlies black-necked crane's unusual escape from an extinction vortex

N. Cui, X. Ma, H. Wu, X. Chen, C.-M. Hung, L. Zhang, F. Lei, L. Yang, D. Yan, X. Yang, F. Dong

This study shows black-necked cranes rapidly recovered from a population bottleneck through genetic purging of deleterious mutations, escaping an extinction vortex.

bioRxiv · Apr 18, 2024 · PreprintEvolutionary Biology

Structural basis for ssDNA-activated NADase activity of the prokaryotic SPARTA immune system

J.-T. Zhang, X.-Y. WeiWei, N. Cui, R. Tian, N. Jia

The paper determines the structure of the SPARTA immune system, revealing how it activates NADase activity in response to ssDNA targets.

bioRxiv · Jul 14, 2023 · PreprintBiochemistry

Effect and mechanism of black soybean peptides alleviating oxidative damage in the celiac disease cell model

C. Cui, N. Wang, E. Gao, Q. Yu, X. Sun, M. Hu, Q. Xu, N. Cui, Y. Zheng, F. Wang, C. Wang

This study investigates how black soybean peptides alleviate oxidative damage caused by alpha gliadin peptide in a celiac disease cell model.

bioRxiv · Sep 19, 2022 · PreprintCell Biology

Structural rearrangements of a caspase-like protease TPR-CHAT govern virus-host discrimination during type III-E CRISPR-Caspase immunity

N. Cui, J.-T. Zhang, Z. Li, X.-Y. Liu, C. Wang, H. Huang, N. Jia

The paper reports cryo-EM structures of gRAMP-crRNA and gRAMP-crRNA-TPR-CHAT complexes, revealing how TPR-CHAT discriminates between self and non-self RNA targets through conformational changes.

bioRxiv · Sep 3, 2022Biochemistry

The response mechanism of oreorchis patens (Lindl.) Lindl. to cold stress

L. Yu, Y. Xu, Y. Zhang, M. Shao, Q. Miao, X. Chen, H. Yang, N. Cui, B. Qu

This study investigates how Oreorchis patens responds to cold stress by analyzing physiological, biochemical, and molecular mechanisms, identifying differentially expressed genes and confirming their roles through qRT-PCR.

bioRxiv · Jul 25, 2022 · PreprintPlant Biology

CSF1R inhibition by small molecule affects T-helper cell differentiation independently of microglia depletion

F. Lei, N. Cui, C. Zhou, J. Chodosh, D. D. Vavvas, E. I. Paschalis

This study shows that CSF1R inhibition affects T-helper cell differentiation in CD4+ cells, independent of microglia depletion.

bioRxiv · Dec 21, 2021 · PreprintImmunology

Hydroxide ions amplified by water entanglement underly the mechanism of general anesthesia

S. Zhang, H. Qian, N. Li, L. Yang, Y. Xu, R. Chen, D. Lu, R. Zhao, H. Liu, N. Cui, Q. Liu

This study shows that inhaled anesthetics reduce neural excitability by disrupting multiple-water entanglement networks, which amplify hydroxide ion concentration changes.

bioRxiv · Jan 28, 2021 · PreprintAnimal Behavior & Cognition

Tuning the course of evolution on the biophysical fitness landscape of an RNA virus

A. Rotem, A. Serohijos, C. Chang, J. Wolfe, A. Fischer, T. Mehoke, H. Zhang, Y. Tao, L. Ung, J.-M. Choi, A. Kolawole, S. Koehler, S. Wu, P. Thielen, N. Cui, , E. Shakhnovich

This study predicts the evolutionary pathway of norovirus escaping antibodies using a biophysical fitness model, validated by experimental evolution in bulk culture and microfluidics.

bioRxiv · Dec 8, 2016Evolutionary Biology