K. Yang

This study investigates the radiosensitizing effect of curcumin combined with Glu-GNPs on breast cancer xenografts in nude mice, showing reduced VEGF and HSP90 expression.

The paper shows that IMD/Relish suppresses perilipin1, leading to lipid droplet enlargement that reduces ROS stress during bacterial infection in Drosophila.

This study shows Carmofur inhibits SARS-CoV-2 main protease by covalently binding to Cys145 and occupying the S2 subsite, with an EC50 of 24.30 M in cell-based viral replication assays.

This paper develops freeze-dried PCR mixes for SARS-CoV-2 detection that can be stored at room temperature, maintaining sensitivity and specificity for up to 28 days.

The paper identifies a mechanism-based inhibitor of the COVID-19 virus main protease through structure-assisted drug design and high-throughput screening.

This study identifies a PAF1C-dependent pathway that restores transcription elongation after DNA damage repair in human cells.

This paper identifies and characterizes 359 RXLR effectors in nine Pythium species, revealing evolutionary patterns and functional roles in host interactions.

PIRD is a database that collects and stores annotated TCR and BCR sequencing data, along with tools for visualization and analysis.

This study evaluates the methodological quality of animal studies using the SYRCLEs risk of bias tool, finding significant differences between Chinese and English studies.

The paper develops a method to upscale biodiversity-ecosystem functioning relationships using macroecological patterns, showing that species-area and biomass-area curves predict biodiversity-biomass relationships at larger scales.

The paper shows that spindle asymmetry, regulated by CDC42 signaling and microtubule tyrosination, enables non-Mendelian chromosome segregation during female meiosis.

The paper assesses the Three-North Afforestation Program's first 30 years, finding increased forest area but declining quality, limited desertification reduction, and low shelterbelt coverage.