L. Ding

This study shows that IgT is the main immunoglobulin induced in trout skin mucosa during bacterial infection, with SALT serving as a key inductive site.

This study identifies Aqp5 as a key factor in IPMN development using a novel mouse model, linking nuclear GSK-3β and oncogenic KRas to terminal duct cell expansion.

This study identifies potent human neutralizing antibodies against SARS-CoV-2 from convalescent patients, with some showing high efficacy in blocking viral entry.

This study uses mechanistic simulations to predict transdermal fentanyl delivery, showing significant variability in uptake by age and anatomical location, and demonstrating the potential of micron-sized reservoirs to enhance drug flux.

This paper develops a rapid, low-cost method to detect and quantify SARS-CoV-2 virus particles using nanoplasmonic sensors in microplate readers and smartphone devices.

This study uses a tumor-on-a-chip platform to show that M1 macrophages inhibit tumor growth and angiogenesis, while M2 macrophages promote tumor migration and angiogenesis through distinct molecular mechanisms.

This paper develops an electronic blood vessel using flexible bio-degradable circuitry to enhance endothelization and enable gene delivery, showing good biocompatibility and patency in a rabbit model.

This study investigates the role of maize PIP2;5 aquaporin in regulating stomatal closure during water deficit and ABA treatment, showing it enhances water conservation by modulating ROS and stomatal conductance.

GC4419 enhances tumor killing when combined with stereotactic ablative radiation in NSCLC and other cancers by generating hydrogen peroxide and altering inflammatory signaling.

This study identifies a novel adipocyte subtype using single-nucleus RNA-Seq that regulates thermogenesis via paracrine signaling in humans and mice.

This study identifies and validates a core regulatory circuitry trio in Ewing sarcoma, showing how EWS-FLI1 and CRC factors regulate transcription and epigenome, with implications for therapy.

The paper introduces GLAMS, a method using glycosyltransferase labeling and mass spectrometry to identify sialylation linkages at the glycopeptide level, successfully identifying 1,236 linkage-specific sialoglycopeptides from human serum.

This study investigates how CXCL12 affects human sperm motility and chemotaxis through its receptors CXCR4 and CXCR7, finding CXCR4 is the dominant mediator.

The paper tests the reproducibility of PDX drug responses and sequence results across different labs using standardized protocols and workflows.

This study shows that 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic mice by scavenging reactive dicarbonyls and improving HDL function.

This study isolates and characterizes Bacillus velezensis DTU001, demonstrating its broad antifungal activity against human and plant pathogens, superior to individual lipopeptides.

This paper reports a case of C. deuterogattii VGIIa infection in a U.S. patient linked to travel to the PNW outbreak region and associated with anti-GM-CSF autoantibodies.

This study identifies EZH2 as a p53 mRNA-binding protein that enhances translation of gain-of-function p53 mutants, promoting cancer growth and metastasis, and shows that inhibiting EZH2 causes synthetic lethality in these cells.