M. Ouyang

Os-circANK negatively regulates resistance to bacterial blight in rice via Osa-miR398b/OsCSD1/OsCSD2 pathways

The paper identifies Os-circANK as a circRNA that suppresses rice resistance to bacterial blight by sponging Osa-miR398b and modulating OsCSD1/OsCSD2 expression.

Amphiphilic particle-stabilized nanoliter droplet reactors with a multi-modal portable reader for distributive biomarker quantification

This paper develops a portable droplet reactor system for biomarker quantification in resource-limited settings, achieving low detection limits and comparable accuracy to ELISA.

Cell Dynamic Mechanics Regulates Large-spatial Isotropic Matrix Modeling with Computational Simulations

The paper uses computational simulations to study how cell mechanics regulate isotropic collagen matrix modeling at large spatial scales, revealing key cellular mechanisms involved.

Mechanical communication-induced cell directional migration and branching connections mediated by calcium channels, integrin β1 and N-cadherin

The paper investigates how mechanical communication between cells leads to directional migration and branching connections, mediated by calcium channels, integrin β1, and N-cadherin.

Transcription factor FOXM1 specifies the loading of chromatin DNA to extracellular vesicles

This study identifies FOXM1 as a transcription factor that specifies and loads chromatin DNA fragments into extracellular vesicles via an LC3-dependent autophagosome-MVB pathway.

Deficits in seizure threshold and other behaviors in adult mice without gross neuroanatomic injury after late gestation transient prenatal hypoxia

This study shows that late gestation transient prenatal hypoxia in mice leads to long-term functional deficits without gross anatomical brain damage.

Cell-extracellular matrix interactions in the fluidic phase direct the topology and polarity of self-organized epithelial structures

This study shows that cell-ECM interactions in the fluidic phase determine epithelial structure topology and polarity through ECM topology and biomechanical cues.

Cell motion-coordinated fibrillar assembly of soluble collagen I to promote MDCK cell branching formation

The paper shows MDCK cells coordinate collagen I fiber assembly through motion, promoting branching morphogenesis, with cell contraction and actin cytoskeleton playing key roles.

Monodisperse drops templated by 3D-structured microparticles

This paper demonstrates a method to create uniform sub-nanoliter compartments using 3D-structured microparticles, enabling stable monodisperse drops without specialized equipment.

Formation of uniform reaction volumes using concentric amphiphilic microparticles

The paper develops a method to create uniform microscale reaction compartments using amphiphilic microparticles, enabling scalable and multiplexed assays with high sensitivity.

Sensing Traction Force on Matrix Induces Cell-Cell Distant Mechanical Communications for Self-assembly

This study shows cells can sense long-range biomechanical forces through the matrix to initiate distant mechanical communication, enabling coordinated self-assembly.