Author

P. Fu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:DNA methylation· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Y. Chen· 2 shared Y. Liu· 2 shared Y. Peng· 2 shared B. Xia· 1 shared F. Yu· 1 shared H. Cheng· 1 shared H. Liu· 1 shared H. Ma· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

Y. Chen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural Basis for RNA-guided DNA degradation by Cas5-HNH/Cascade complex

H. Zhu, H. Zhang, Y. Liu, L. Wang, Q. Zhang, P. Fu, L. Zhang

This study presents cryo-EM structures of the Cas5-HNH/Cascade complex, revealing its DNA cleavage mechanism and the role of zinc-finger and divalent ions in enzyme activity.

bioRxiv · Jul 22, 2024Biophysics

Distinct functions of EHMT1 and EHMT2 in cancer chemotherapy and immunotherapy

Z. Kang, P. Fu, H. Ma, T. Li, K. Lu, J. Liu, V. Ginjala, P. Romanienko, Z. Feng, M. Guan, S. Ganesan, B. Xia

This study shows EHMT1 and EHMT2 have distinct roles in cancer therapy, with EHMT1 affecting DNA replication and alkylating agents, while EHMT2 influences immunotherapy response via STING expression.

bioRxiv · Oct 3, 2023 · PreprintCancer Biology

Long-B prokaryotic Argonaute systems employ various effectors to confer immunity via abortive infection

X. Song, S. Lei, S. Liu, Y. Liu, P. Fu, Z. Zeng, K. Yang, Y. Chen, M. Li, Q. She, W. Han

The paper identifies long-B prokaryotic Argonaute systems as cell suicide mechanisms that use effector proteins to eliminate invading nucleic acids through abortive infection.

bioRxiv · Mar 9, 2023 · PreprintMicrobiology

Plant Virus Database: a resource for exploring the diversity of plant viruses and their interactions with hosts

H. Wu, P. Fu, Q. Fu, Z. Zhang, H. Zheng, L. Mao, X. Li, F. Yu, Y. Peng

The paper builds a comprehensive Plant Virus Database (PVD) containing 3,206 virus species and 9,604 host interactions, revealing significant virome differences between plant groups and regions.

bioRxiv · Mar 20, 2022 · PreprintMicrobiology

Transcription factor FOXM1 specifies the loading of chromatin DNA to extracellular vesicles

Y. Zhang, N. Ding, Y. Li, X. Zhao, S. Yang, P. Fu, Y. Peng, H. Cheng, M. Ouyang, R. Wang, Y. Wang, H. Liu, Y. Chen, X. Huang, L. Yu, Y. Tan

This study identifies FOXM1 as a transcription factor that specifies and loads chromatin DNA fragments into extracellular vesicles via an LC3-dependent autophagosome-MVB pathway.

bioRxiv · Jan 27, 2022 · PreprintCell Biology