S. Basu

This paper uses molecular dynamics simulations to study how Sr2+ doping affects fibronectin adsorption on HA surfaces, finding enhanced adhesion and structural flexibility but no impact on RGD motif availability.

The paper investigates the disorder-to-order transition in the SARS-CoV-2 Spike protein upon Furin binding, highlighting salt-bridge networks and their role in proteolytic cleavage efficiency.

The paper investigates two CLas effectors, P235 and Effector 3, showing they suppress citrus innate immune responses and contribute to HLB pathogenesis by inhibiting immune proteins and inducing cell death.

This study shows that chewing herbivores interact with soil rhizobia through plant-mediated pathways, affecting both herbivore feeding and rhizobial symbiosis.

This study identifies PTPN14 as a stabilizer of SMAD4, enhancing BMP9 signaling in endothelial cells and suggesting potential drug targets for HHT.

This study identifies amyloid and amyloid-like structures in plant seed storage protein bodies (SSPB) and demonstrates their role in controlling germination and seedling growth.

This study identifies four small molecule inhibitors of SARS-CoV-2 nsp14 RNA cap methyltransferase, with three showing synergy with remdesivir in antiviral assays.

This study shows Mycobacterium tuberculosis uses its DosS sensor kinase to detect H2S via Fe3+ heme binding, activating the dormancy regulon.

This paper controls dendritic crystallization and bacterial distribution in drying respiratory droplets using vapor-mediated interactions to manipulate flow dynamics and solute transfer.

The paper discovers small molecule inhibitors of alkaline ceramidase 3 using fluorescent substrates and characterizes their mechanism of action.

This paper introduces an automated platform for structural analysis of membrane proteins using serial crystallography, enabling high-throughput ligand discovery and structural determination.

This study shows that evaporation-induced bacterial patterns on fomites enhance Salmonella Typhimurium virulence through hyper-proliferation in macrophages and sustained pathogenicity in mice.

This study identifies S6K2 as a vulnerability in MAPK inhibitor-resistant NRAS-mutant melanoma, showing its abrogation disrupts lipid homeostasis and triggers cell death.

This study identifies patulin and aurintricarboxylic acid as inhibitors of SARS-CoV-2 nsp14 exoribonuclease, showing antiviral activity in cell culture.

This study shows that plant responses to multiple antagonists depend on attack order and phytohormone interactions, with some interactions being antagonistic and others synergistic.

The paper shows predators affect plant virus transmission through both direct consumption of aphids and indirect effects on aphid behavior and movement.

This study uses molecular dynamics simulations to investigate how electric fields affect fibronectin adsorption on hydroxyapatite surfaces, revealing changes in protein structure and interactions.

The paper presents a cryo-EM structure of an NER initiation complex involving Rad4-Rad23-Rad33 and TFIIH bound to a DNA lesion, revealing DNA unwinding and translocation mechanisms.

This study examines how extracellular and intracellular mycobacteria invade the blood-retinal barrier in a zebrafish model of ocular TB, showing different disease progression outcomes based on invasion mode.

The paper shows that inhibiting MMP2 on extracellular vesicles reduces miR-122 transfer to macrophages, thereby decreasing liver inflammation.

This study shows that de novo phosphatidylcholine synthesis via CEPT is essential for promastigote survival but not required for amastigote virulence or replication.

This study examines how orchard management and landscape context influence bacterial and fungal communities in pear flowers, revealing distinct effects on diversity and distribution of microbial taxa.

The paper shows that temporal and spatial regulation of pathway sensors and cross-pathway feedback control the fMAPK pathway in yeast.

The paper shows lipid droplets promote Ago2 phase separation, reduce Dicer1 levels, and decrease miR-122 activity in hepatic cells under lipotoxic stress.

The paper shows that inhibitory phosphorylation of CDK and PP2A synergistically regulate cell size homeostasis, and DNA concentration reduces CDK activity in diploid cells.

This study analyzes single-cell RNA and TCR profiles from AML patients before and after PD-1 blockade therapy to identify factors influencing response and resistance.

The paper uses 4-PHF parameters to classify onion seedlots into storability groups, finding AUC as crucial for accurate categorization beyond conventional germination metrics.

This study quantifies LSDV acquisition and retention by vector insects and models transmission, finding clinical cattle are key promoters of viral spread and highlighting the need for targeted control strategies.

This study uses live-cell 3D single-molecule tracking to show that the NuRD complex decompacts chromatin and alters enhancer dynamics by increasing their movement and reducing time in a fast-diffusing state.

This study investigates adaptive evolution in mitochondrial genomes of intertidal chitons by analyzing protein-coding genes and their functional implications in energy metabolism.