T. Zheng

This study identifies key MRI acquisition factors affecting fetal brain morphology and shows that ComBat-GAM harmonization effectively reduces site effects while preserving developmental patterns.

This study investigates the structural and interaction details of Efg1's prion-like domains during phase separation in Candida albicans, revealing helical structures and residue-specific interactions critical for the transcriptional switch between white and opaque cell states.

The paper analyzes single-cell transcriptomes of pig skin from six anatomical regions to characterize cellular heterogeneity and identify candidate genes for ECM accumulation.

This study tracks memory T follicular helper cells and antibody response after three doses of CoronaVac vaccine over 300 days, showing increased neutralizing antibodies and cTFH cells, with correlation between cTFH and antibody titers.

This study investigates how angiotensin II affects the gut microbiome in mice, finding its impact is smaller than factors like diet and facility.

This study quantifies the intra-host mutation rate of SARS-CoV-2 during acute infection and finds higher mutation rates in viruses with NSP-14 mutations and in immunocompromised patients.

This study shows that GPR41/43 receptors regulate blood pressure by maintaining gut barrier integrity and preventing renal inflammation through TLR4 signaling.

The paper maps plant trait variability across different spatial resolutions in the Western Ghats using imaging spectroscopy and identifies environmental drivers of trait variation.

The paper establishes a stable human cell line as a reference for transcriptomic and proteomic studies, showing consistent results across generations and platforms.

The paper constructs a computational model of the nuclear pore complex to explain how it avoids clogging and improves transport efficiency in crowded conditions.

This paper introduces PRIME-PAINT, a method for multiplexed fluorescence nanoscopy with millimeter-scale field-of-view and high resolution, demonstrating its use on biological samples.

This study investigates how alkanediols, particularly 1,6-hexanediol, disrupt FUS phase separation using multiple techniques and identifies factors like geometry and hydrophobicity that influence their effectiveness.

The paper introduces a framework and software for optimizing and reproducibly analyzing multiplex imaging data, focusing on cyclic immunofluorescence.

ZF2001, a tandem-repeat dimeric RBD protein vaccine, induces strong immune responses and protects mice and non-human primates from SARS-CoV-2 infection.

This study identifies previously uncharacterized interactions between folded and disordered domains of UBQLN2 that asymmetrically modulate its phase separation behavior.

This study evaluates a recombinant chimpanzee adenovirus vaccine expressing a dimeric tandem-repeat RBD of SARS-CoV-2, showing enhanced immune responses and protection in mice.

The paper shows that bacterial DNA recombination increases tRNA levels early in antibiotic stress, aiding resistance before efflux pumps or mutations.

This study isolates and characterizes testicular extracellular vesicles, identifies their cargo, and shows their role in inter-compartmental communication during spermatogenesis.

The paper identifies the interactomes of ER ribosome-binding proteins, revealing distinct molecular environments and functional roles for SEC62 and LRRC59 in ER redox regulation and mRNA translation.

This study identifies dynamic surface and secreted proteins of Aspergillus fumigatus conidia under different conditions and compares them to other allergenic molds.

This study shows that vimentin intermediate filaments provide cytoplasmic mechanics that enhance strength, stretchability, resilience, and toughness under severe deformations.