Author

X.-L. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Cancer Biology· 1 Ecology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Organism:fungi (other)· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

L. Zheng· 2 shared Y.-Z. Zhang· 2 shared Z. Ren· 2 shared A. Hendy· 1 shared B. Rihtman· 1 shared B. Tang· 1 shared B. Wu· 1 shared C. Gao· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPathology

L. Zheng

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Doxorubicin inhibits phosphatidylserine decarboxylase and confers broad-spectrum antifungal activity

Y. Zhou, J. Zhao, L. Yang, R. Bi, Z. Qin, P. Sun, R. Li, M. Zhao, Y. Wang, G. Chen, H. Wan, L. Zheng, G. Wang, X.-L. Chen, Q. Li, G. Li

The paper shows doxorubicin inhibits MoPSD2, a phosphatidylserine decarboxylase in Magnaporthe oryzae, reducing fungal growth and crop disease severity.

bioRxiv · Apr 7, 2023Pathology

Nanosecond pulsed electric field ablates rabbit VX2 liver tumors in a non-thermal manner versus radiofrequency ablation

Q.-G. Li, Z.-G. Liu, Y. Sun, Y.-W. Zou, X.-L. Chen, B. Wu, X.-H. Chen, Z. Ren

This study compares nanosecond pulsed electric field (nsPEF) and radiofrequency ablation (RFA) in treating rabbit VX2 liver tumors, showing nsPEF induces apoptosis and non-thermal ablation.

bioRxiv · Aug 16, 2022 · PreprintCancer Biology

The Magnaporthe oryzae MAP kinase Pmk1 regulates polycomb repressive complex 2 to reprogram genes expression for biotrophic growth

X. Cai, B. Tang, A. Hendy, Z. Ren, C. Liu, M. Kamran, J. Xing, L. Zheng, H. Liu, J. Huang, X.-L. Chen

This paper identifies PRC2-mediated epigenetic repression as critical for regulating gene expression during biotrophic growth in M. oryzae, with Pmk1 coordinating this process by modulating Suz12.

bioRxiv · Apr 20, 2021 · PreprintMicrobiology

Novel enzyme for dimethyl sulfide-releasing in bacteria reveals a missing route in the marine sulfur cycle

C.-Y. Li, X.-J. Wang, X.-L. Chen, Q. Sheng, S. Zhang, P. Wang, M. Quareshy, B. Rihtman, X. Shao, C. Gao, F. Li, S. Li, Y. Chen, Y.-Z. Zhang

The paper identifies a novel ATP-dependent DMSP lysis pathway in bacteria, revealing a new route in the marine sulfur cycle through the enzyme AcoD.

bioRxiv · Oct 29, 2020 · PreprintEcology

PacC-dependent adaptation and modulation of host cellular pH controls hemibiotrophic invasive growth and disease development by the rice blast fungus

X.-L. Chen, D. He, C. Yin, J. Yang, J. Sun, D. Wang, M. Xue, Z. Li, Z. Peng, D. Chen, W. Zhao, J.-R. Xu, N. J. Talbot, Y.-L. Peng

This study identifies the PacC-dependent pH signaling pathway in the rice blast fungus Magnaporthe oryzae, showing it regulates host pH changes and the switch between biotrophic and necrotrophic growth, essential for disease development.

bioRxiv · Jun 22, 2020 · PreprintMicrobiology

Structural visualization of septum formation in Staphylococcus warneri using atomic force microscopy

H.-N. Su, K. Li, X.-X. Yuan, M.-Y. Zhang, S.-M. Liu, X.-L. Chen, L.-N. Liu, Y.-Z. Zhang

This study uses microscopy techniques to reveal the structural features of the septum in Staphylococcus warneri, showing it is composed of two layers with concentric peptidoglycan rings.

bioRxiv · May 24, 2020Biophysics