B. Sun

This study reveals that the nuclear localization sequence of hnRNPA1 forms the core of amyloid fibrils and interacts with Kap{beta}2 to stabilize them, linking nucleo-cytoplasmic transport to neurodegeneration.

The paper shows that MYB31 activation and CBG expression in the pericarp of C. chinense leads to high capsaicinoid accumulation, explaining the extreme pungency of these peppers.

This study compares the therapeutic effects of Remdesivir and Au22Glutathione18 in COVID-19 golden hamsters, finding that the gold compound better suppresses viral replication and inflammation.

The paper quantifies how individual cell behaviors contribute to multicellular synchronization through information transfer in endothelial cell monolayers.

This study investigates the structural factors influencing calcium binding in alpha parvalbumins, finding that both local and non-local protein properties contribute to Ca2+ affinity and Mg2+ selectivity.

The paper reports the crystal structure of PbSRD5A and provides biochemical insights into the conserved mechanism of steroid 5-reductase catalysis.

The paper identifies differentially expressed genes and proteins in liver clear cell foci (CCF) and finds that reduced expression of STBD1 and USP28 is unlikely to explain glycogen overload.

This study uses reaction-diffusion simulations to show that confinement and charge effects in narrow extracellular spaces influence the kinetics of coupled nucleotidase reactions.

The paper identifies IL-24 as an anti-apoptotic factor in liver ER stress, showing its role in preventing cell death and its clinical relevance in acute liver failure.

This study examines how century-long fertilization affects microbial community succession and assembly mechanisms in grassland soils.

This paper develops a 96-well platform of cardiac microtissues to measure contractile force for drug screening and tissue engineering.

The paper compares nitrogen allocation in leaves of nitrogen-fixing and non-nitrogen-fixing tree species, finding lower photosynthetic nitrogen use efficiency in nitrogen-fixing species due to reduced allocation to Rubisco and bioenergetics.

This paper develops a platform to multiplex profile single-cell EV secretion, revealing heterogeneity in EV phenotypes and secretion patterns in OSCC cells.

The paper identifies a late B lymphocyte response linked to renal dysfunction and fibrosis following kidney injury and transplantation.

This study shows that T7 helicase can restart DNA replication from an RNA transcript without replication restart proteins or primase.

This study uses computational modeling to investigate how electrostatic interactions and conformational dynamics influence the binding of calcineurin’s disordered domain to calmodulin.