Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
L. Gasiorowski, C. Chai, A. Rozanski, G. Purandare, F. Ficze, A. Mizi, B. Wang, J. C. Rink
This study shows that whole-body regeneration in a flatworm occurs without conventional neoblasts, challenging the idea that neoblasts are essential for regeneration.
bioRxiv · May 24, 2024Zoology
R. N. Hall, H. Li, C. Chai, S. Vermeulen, R. Rio, E. S. Song, J. Gibson, M. Prakash, A. Z. Fire, B. Wang
This paper develops a toolkit for live imaging of whole-body regeneration in flatworms, revealing neuron regenerative limitations and independent nerve cord reconnection.
bioRxiv · Apr 28, 2024 · PreprintBioengineering
R. N. Hall, U. Weill, L. Drees, S. Leal-Ortiz, H. Li, C. Chai, A. Sanchez Alvarado, N. A. Melosh, A. Fire, J. C. Rink, B. Wang
This paper demonstrates heterologous protein expression in planarians using mRNA transfection, improving reporter expression through UTR optimization and codon bias.
bioRxiv · Apr 20, 2021Bioengineering
H. Li, D. Krishnamurthy, E. Li, P. Vyas, N. Akireddy, C. Chai, M. Prakash
Squid provides an affordable, open-source imaging platform with modular hardware and software for deploying advanced microscopy techniques in research and low-resource settings.
bioRxiv · Dec 28, 2020 · PreprintBioengineering
B. W. Q. Tan, S. Tan, B. W. L. Tan, S. Navakkode, C. Y. Ng, S. Yuan, M. C. Liang, C. Liu, S. Yin, C. Chai, K. C. M. Chew, Y. K. Tai, S. Sreedharan, Y. Lam, P. Liao, , T. W. Soong
This study identifies mTOR S-nitrosylation as a kinase-independent mechanism that suppresses autophagy and lysosomal proteolysis, with implications for Alzheimer's disease.
bioRxiv · Sep 11, 2020 · PreprintCell Biology
J. Zhong, G. Tang, J. Zhu, X. Qiu, W. Wu, G. Li, X. Lin, L. Liang, C. Chai, Y. Zeng, F. Wang, L. Luo, J. Li, F. Chen, Z. Huang, , D. Chen
This study profiles single-cell epigenomic and transcriptomic data from Parkinson's disease mouse brain to identify early biomarkers and cellular contributions to disease pathology.
bioRxiv · Feb 4, 2020 · PreprintCell Biology
Y. Yang, N. Lang, H. Zhang, L. Zhang, C. Chai, W. Jiang, Y. Gu
This study identifies sr8384, a novel small noncoding RNA in Clostridium acetobutylicum, which regulates growth and solvent synthesis, and shows its functional conservation in another clostridial species.
bioRxiv · Jun 8, 2019 · PreprintMicrobiology
J. Zhong, D. Chen, F. Hu, F. Chen, Z. Xu, J. Fang, J. Xu, S. Wang, L. Liang, C. Chai, X. Ding, J. Zhu, P. Ding, J. Xia, S. Jiang, , X. Sun
This study uses single-cell RNA-seq to analyze human infant retina, identifying cell types, communication networks, and developmental changes, providing a resource for retinal research and regenerative medicine.
bioRxiv · Apr 25, 2019 · PreprintCell Biology
J. Wu, X. Ding, F. Hu, Z. Xu, S. Zhang, L. Liang, C. Chai, J. Zhong, S. Wang, X. Lin, Y. Chen, Q. Feng, J. Zhu, S. Jiang, J. Xia, , F. Chen
This study uses single-cell RNA sequencing to analyze the cellular diversity and molecular markers in the retina of a trisomy 21 fetus, revealing communication networks and novel markers.
bioRxiv · Apr 21, 2019 · PreprintCell Biology